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Keywords: Fibrin
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Pathophysiology of Haemostasis and Thrombosis (1993) 23 (3): 149–158.
Published Online: 28 April 2009
... as compared to normal adult values. The kinetics of fibrin gel formation was decreased in newborn as compared with normal adult plasmas (gelation rates 2.2 ± 1 vs. 5.6 ± 0.5 × 10 -4 OD/s, lag time 128 ± 25 vs. 72 ± 3 s). The release rates of fibrinopeptide A (FPAp ± FPA) and fibrinopeptide B (FPB) were...
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1991) 21 (Suppl. 1): 73–79.
Published Online: 24 April 2009
... desulphatohirudin, in large quantities this is now under investigation. A new model of arterial thrombosis in rats is described where a thrombus is formed on a mechanically injured vessel in vivo. Both platelet and fibrin deposition is inhibited by a recombinant hirudin (CGP 39393) at doses which prolong...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1987) 17 (4): 189–194.
Published Online: 23 April 2009
...Marcus E. Carr Recent studies have reported an interaction of albumin with polymerizing fibrin, resulting in a narrowing of gel fibers. It has been postulated that albumin interacts with the E domain resulting in delayed and thus altered polymerization. Utilizing turbidity techniques, the impact...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1988) 18 (2): 117–125.
Published Online: 23 April 2009
... of fibrin resulted in a decrease in K m , whereas the presence of larger amounts of fibrin resulted in an increase in k cat with a slight decrease in K m . The presence of fibrinogen also enhanced the activation of Glu-Plg by t-PA with an increase in k cat and without change in K m . When the effects...
Journal Articles
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1984) 14 (2): 170–178.
Published Online: 21 April 2009
... in normal plasma the parameters that define the gelation of fibrin as measured by turbidity curves and their variation according to the fibrinogen concentration. This permits us to establish the kinetics of fibrin gel formation and normal range values. 1 06 1983 30 11 1983 21 4 2009 ©...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1983) 13 (1): 25–35.
Published Online: 17 April 2009
... to thrombus formation. Uptake was assessed by means of radioisotopic analysis and autoradiography. The plasminogen was taken up by thrombi during and after their formation. The largest percentage was in the fibrin component. ε-Aminocaproic acid-blocking experiments confirmed the specificity of plasminogen...
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1976) 5 (4): 193–210.
Published Online: 16 April 2009
...J.J. Emeis; J. Lindeman Disseminated intravascular coagulation was induced in rats by injection of a silver colloid suspension or thrombin. Ten min after the injection of colloid, fibrin deposits were observed light microscopically in all major organs. At 30 min, fibrin was no longer present...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1977) 6 (4): 236–243.
Published Online: 16 April 2009
...J.E. Dyr; Z. Vorlová; Z. Vodrážka Two peaks were demonstrated after gel chromatography on Sepharose 6-B of noncovalently bonded fibrin dissolved in 1 M NaBr at pH 5.3. One was eluted at the void volume while the other one was eluted at the elution volume of fibrinogen. Both fractions were stable...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1973) 2 (5): 181–188.
Published Online: 15 April 2009
.... The purified human thrombin slowly lysed fibrin in a manner different from that of plasmin and in addition to the release of peptides A and B. This activity may be responsible for some of the apparent heterogeneity of fibrinogen in vivo . 21 11 1973 29 11 1973 15 4 2009 © 1973 S. Karger...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1999) 29 (1): 50–57.
Published Online: 13 September 1999
...), is influenced by the clotting factors (except XII and XIII), the activated protein C system and natural inhibitors on the one hand and by platelet activity on the other. The platelet reactions that we found to be involved are induced by thrombin via glycoprotein (GP) IIb/IIIa activation and by fibrin via...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1998) 28 (6): 289–300.
Published Online: 11 August 1999
... in cytosolic [Ca 2+ ] i , is accompanied by formation of membrane blebs, and stimulates the formation of thrombin from its precursor prothrombin. Here, we investigated whether thrombin, as a potent platelet agonist, can induce this procoagulant response in plasma-free platelets interacting with fibrin...