...N. Kokolis; C. Rekkas; M. Tsandarliotou; A. Smokovitis The effect of aspirin or endotoxin or aspirin plus endotoxin on the circadian variations of plasminogen activator activity (PAA), tissue-type plasminogen activator (t-PA) antigen level, plasminogen activator inhibition (PAI) and plasmin...

...Ralf Scherer; Ulrich Schmidt; Wolfgang Kox; Dietrich Paar Endotoxin infusion (lipopolysaccharide from Escherichia coli 120 μg kg –1 i.v.) was titrated to produce hypercoagulability in rabbits and the effects of prostacyclin (PGI 2 ) treatment (continuous infusion of 6 ng kg –1 min –1 i.v...

...A. Bernat; M. Sainte-Marie; C. Roque; V. Ingelaere; J.P. Maffrand; J.M. Herbert Procoagulant activity of the endothelium and of monocytes was induced by an intravenous administration of a low dose of endotoxin in the rabbit. Venous thrombosis induced by a 45-min stasis of the jugular vein...

... (TNF) at the doses of 0.8 μg/kg/h (n = 5) and 8 μg/kg/h (n = 3) or with endotoxin (8 μg/kg/h, n = 7). Animals infused with vehicle (n = 11) served as control group. Plasminogen activator (PA) activity of glomerular extracts from rabbits infused with 8 μg/kg/h of TNF or endotoxin was significantly lower...

...B. Østerud; A. Tindall; J.O. Olsen A study was carried out on the effect of high doses of methylprednisolone to rabbits in combination with or after challenging them with Escherichia coli endotoxin. The animals given steroids simultaneously with the endotoxin or 2–6 h thereafter all had...

...G. Nowak; F. Markwardt Various reactions of disseminated intravascular coagulation (DIC) were experimentally induced by infusion of thrombokinase in rats, by administration of endotoxin in rabbits and pigs and by infusion of adrenaline and thrombin in dogs. Low plasma concentrations of recombinant...

... between the levels of monocyte tissue factor (MTF) and levels of circulating fibrinopeptide A (FPA), a marker of in vivo clotting activation. Furthermore, monocytes from cancer patients have a greater procoagulant response to stimulation by endotoxin in vitro, which appears independent of lymphocyte...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Complement Coagulation Thromboplastin Monocytes Endothelial cells Endotoxin 19 06 1984 7 09 1984 21...

...Toshikazu Yoshikawa; Masashi Murakami; Yasumasa Furukawa; Shuhei Takemura; Motoharu Kondo An experimental model of disseminated intravascular coagulation (DIC) could be induced by a sustained infusion of 100 mg/kg of endotoxin for 4 h. Using this experimental model of DIC, the preventive effect...

...Toshikazu Yoshikawa; Yasumasa Furukawa; Masashi Murakami; Shuhei Takemura; Motoharu Kondo Experimental disseminated intravascular coagulation (DIC) can be induced by 4 h sustained infusion of endotoxin at a dose of 100 mg/kg in rats. The experimental model of DIC in rats was used to study...

...Toshikazu Yoshikawa; Masashi Murakami; Yasumasa Furukawa; Haruki Kato; Shuhei Takemura; Motoharu Kondo The effects of FUT-175 (6-amidino-2-naphthyl-4-guanidino benzoate-dimethanesulfonate), a new synthetic protease inhibitor, on endotoxin-induced experimental disseminated intravascular coagulation...

...Edward L. Howes, jr.; Donald G. McKay The generalized Shwartzman reaction was produced in rabbits by two intravenous injections of endotoxin given 20–22 h apart. Prior to the second injection of endotoxin, the animals were made hypovolemic by removal of 40% blood volume or reduction of the systolic...

...Sadaaki Iwanaga; Takashi Morita; Toshie Harada; Shin Nakamura; Makoto Niwa; Katsumi Takada; Terutoshi Kimura; Shunpei Sakakibara An endotoxin-activated hemocyte lysate from the horseshoe crab (Tachy-pleus and Limulus) was found to hydrolyze Bz-Ile-Glu-(γ-OR)-Gly-Arg- p -nitroanilide (PNA), Bz-Val...

...Michael J. Gallimore; Ansgar O. Aasen; Egil Amundsen Plasma levels of prekallikrein, kallikrein, high molecular weight kininogen and kallikrein inhibitors were measured in samples from dogs infused with E. coli endotoxin. Markedly reduced levels of prekallikrein and high molecular weight kininogen...

...E. Hiller; J.G. Saal; G. Riethmüller Endotoxin-stimulated monocytes develop a very high tissue-factor-like activity as compared to an equivalent number of monocytes in a preparation of monocyte-enriched mononuclear blood cells obtained by Ficoll®-Urovison® density gradient centrifugation which...