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Keywords: Bleeding time
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Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1993) 23 (5): 249–258.
Published Online: 28 April 2009
... or thrombin-induced platelet aggregation in vitro. In the rat wire coil-induced thrombosis model, a 50% thrombo-protective effect may be brought about with doses of 0.043 μmol/kg of rhirudin and 1.43 μmol/kg of the synthetic peptide. However, doubling of bleeding times is caused, on average, by dosages...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (4): 203–209.
Published Online: 28 April 2009
... protein C (APC) was greater than that by heparin. In this study, we compared the bleeding complication of intravenously administered APC and heparin in rabbits, and also estimated primary hemostasis. When both anticoagulants were intravenously infused, the bleeding time from a punctured ear vein...
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Pathophysiology of Haemostasis and Thrombosis (1997) 27 (2): 99–104.
Published Online: 28 April 2009
... marrow transplantation Bleeding time Thrombostat Platelet aggregometer Abstract A method to determine primary hemostasis ex vivo (Throm­ bostat) was modified to monitor the transfusion effect of plate­ let concentrates (PC) in 12 patients with thrombocytopenia following bone marrow transplantation...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1995) 25 (4): 182–192.
Published Online: 28 April 2009
... of the heart, kidneys, or lungs. Furthermore, bleeding time prolongation induced by bolus application of 3.0 and 30.0 mg/kg r-hirudin was significantly inhibited by APC within 5 min. These results suggest that administration of APC may be an effective way to reverse the effects of r-hirudin in the coagulation...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 1): 159–164.
Published Online: 28 April 2009
... reported to occur within the bleeding time wound and infusion of recombinant FVIIa (rFIIa) has been shown to shorten the bleeding time in rabbits. We have investigated whether infusion of rFVIIa would enhance fibrin formation in bleeding time wounds in patients with thrombocytopenia as reflected...
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Pathophysiology of Haemostasis and Thrombosis (1991) 21 (6): 360–369.
Published Online: 24 April 2009
...A.O. Oyekan; A.O. Onabanjo The possible involvement of platelets in the pathogenesis of malaria was examined by monitoring the changes in platelet function (bleeding time [BT] and thrombin time [TT]) concomitantly with changes in packed cell volume (PCV) and erythrocyte infection rate (EIR...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1991) 21 (Suppl. 1): 80–87.
Published Online: 24 April 2009
...Melitta Just; Dominique Tripier; Dirk Seiffge The effect of recombinant hirudin (r-hirudin; HBW 023) was studied in four different models of thrombosis as well as on bleeding time. Arteriolar thrombus formation was induced in rats either by argon laser injury or by photochemical reaction. r-Hirudin...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1988) 18 (Suppl. 3): 48–54.
Published Online: 23 April 2009
... Medicine, University Hospital, Justus Liebig University, Giessen, FRG Key Words. Unfractionated heparin Low-molecular-weight heparin Platelet function Platelet count Bleeding time Spontaneous platelet aggregation ADP-induced platelet aggregation ADP-induced fibrinogen binding to platelets...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1985) 15 (5): 324–330.
Published Online: 21 April 2009
..., but LMWH at the low dosages tested (0.1 and 0.25 mg/kg) demonstrated significantly higher activity than H. In a rat bleeding time test (transection model) both heparins produced a prolonged bleeding time, but LMWH possessed significantly less potency than H at all the dosages tested. Ex vivo coagulation...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1983) 13 (6): 379–384.
Published Online: 21 April 2009
...M. Small; G.D.O. Lowe; E. Cameron; C.D. Forbes Bleeding time, platelet count and haematocrit were performed in 64 normal, anaemic and polycythaemic subjects with normal renal function and platelet counts over 100 B× 10 9 /l. There was a significant inverse correlation between the bleeding time...
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Pathophysiology of Haemostasis and Thrombosis (1983) 13 (5): 294–300.
Published Online: 21 April 2009
..., on the third and seventh day of treatment with the drug or the placebo. Bleeding time was significantly lengthened by ticlopidine administration. Platelet aggregation, both in vivo and in vitro, was significantly inhibited during the week on ticlopidine. Beta-thromboglobulin concentration was on an average...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1982) 11 (4): 193–203.
Published Online: 17 April 2009
.... The platelet isolation and labelling procedures exerted no certain influence on the aggregation response, and platelet surface/volume calculations did not indicate that platelet activation had taken place. Bleeding time experiments in rabbits indicated that the hemostatic effectiveness of the labelled...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1979) 8 (3-5): 227–233.
Published Online: 16 April 2009
... be converted by the vessel wall to an antiaggregatory substance, whereas it has no proaggregatory effect on platelets. Consistent with these findings Eskimos were found to have a nearly 2-fold longer bleeding time than Danes. Platelet aggregability, too, was merkedly depressed when exposing platelets from...
Journal Articles