...K.T. Preissner The intact vessel wall provides diverse anticoagulant mechanisms which, together with circulating components, are actively and dynamically involved in the regulation of the haemostatic system. These mechanisms are able to specifically and co-operatively counteract various...

.... Extrinsic pathway inhibitor Thromboplastin (tissue factor) Factor VII Coagulation inhibitors Anticoagulants Abstract. Extrinsic pathway inhibitor (EPI) is a Kunitz type serine protease inhibitor. EPI is a potent inhibitor of the factor Vlla/thromboplastin (TP) complex in the presence of factor Xa...

... with factor II deficiency. This distribution pattern can be explained by an inhibitory reaction on factor Ila, which is accelerated by the anticoagulant. In contrast, the pattern of K(2)/K(l) for the activated intrinsic system is identical with the pattern for plasma with factor X deficiency. Qualitative...

..., instructions or products referred to in the content or advertisements. Vitamin K Coumarin Carboxylase Anticoagulants Blood coagulation Haemostasis 16: 239-245 (1986) © 1986 S. Karger AG. Basel 0301-0147/86/0164-0239S2.75/0 Comparison between Hepatic and Nonhepatic Vitamin K-Dependent Carboxylase C...

... Glu residue with the concurrent formation of vitamin K 2,3-epoxide. Coumarin anticoagulants appear to inhibit the microsomal vitamin K epoxide reductase and one of a number of microsomal quinone reductases. They therefore block vitamin K action by preventing the recycling of vitamin K epoxide...

... chloride than to Cuprophane or glass regardless of the anticoagulant used. In citrated plasma, fewer platelets adhered to glass than to Cuprophane, although adhesion to glass and Cuprophane was nearly the same when EDTA or heparin was used as anticoagulant. The number of adherent platelets decreased...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Haemostasis Bleeding time Anticoagulants Rabbit Platelet function...

... platelet responses to wound-generated signals, including ADP, thrombin, and collagen. Anticoagulants disrupt elements of both the intrinsic and extrinsic pathways. Molecular approaches (termed ‘sialomics’) to characterize the full inventory of mRNAs transcribed in salivary glands have revealed a surprising...

... with bleeding problems in the foetus, particularly at the time of delivery. Thus, warfarin has a limited use in the antenatal period and is usually only employed in patients such as those with artificial heart valves who require long-term anticoagulation. However, as warfarin does not cross the breast in any...