... was supported in part by the National Human Genome Research Institute of the National Institutes of Health under award number R21HG012672, and the Program for Precision Medicine in Health Care (PPMH) at the University of North Carolina at Chapel Hill School of Medicine provided funding and institutional support...

...Emily E. Vasquez; Nicole Foti; Caitlin E. McMahon; Melanie Jeske; Michael Bentz; Stephanie Fullerton; Janet K. Shim; Sandra Soo-Jin Lee Introduction: Federal agencies have instituted guidelines to prioritize the enrollment and retention of diverse participants in precision medicine research (PMR...

...Julie A. Beans; Susan B. Trinidad; Erika Blacksher; Vanessa Y. Hiratsuka; Paul Spicer; Erica L. Woodahl; Bert B. Boyer; Cecil M. Lewis Jr.; Patrick M. Gaffney; Nanibaa’ A. Garrison; Wylie Burke Introduction: Precision medicine research investigates the differences in individuals’ genetics...

... to in the content or advertisements. Personalized healthcare Comprehensive genomic profiling Genomics Precision medicine Targeted therapies Oncology Next-generation sequencing Value assessment Broad molecular profiling Value of broad molecular profiling The new paradigm of “personalized...

... significant. All analyses were done using SPSS version 22. Genetic polymorphisms Warfarin Coumarin Precision medicine Dose optimization Warfarin represents the standard of care oral vitamin K antagonist for over 6 decades and still is widely used for prophylaxis and treatment...

... and communication technology Digital health Personalised medicine Precision medicine Personalised healthcare Diagnostics Information Value Discussion Public Health Genomics 2019;22:145 161 DOI: 10.1159/000504785 Received: November 5, 2019 Accepted: November 14, 2019 Published online: December 13, 2019...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cost-effectiveness Modelling Precision medicine Decision analysis Pharmacogenomics...

... Personalized medicine Precision medicine Although family history tools vary in terms of their purpose and attributes [ 11 ], online family history tools (public and patient-facing clinical tools) typically collect the disease history and age at onset for users and their first- and second-degree...

.... Conclusion: Efforts to bring precision medicine to community-based health centers serving minority patients may require multilevel engagement activities to include individuals, providers, health systems, and the community. [email protected] 14 05 2018 14 10 2018 6 12 2018 © 2018 S...

... is a key element of the Precision Medicine Initiative, and the parallel Cancer Moonshot Initiative (CMI) are to improve human health by tailoring medical treatment to the individual characteristics of each patient. The vision of both programs is to use an array of information to identify an individual’s...

...Nadeem Bilani; Michael Dagher; Nathalie K. Zgheib Purpose: As precision medicine continues its expansion into clinical practice and research settings, it is time to investigate genetic and genomic research in the Middle East and North Africa (MENA) region to identify the strengths and deficits...

... of a somatic cell, allowing it to escape the usual controls on its growth. Tumours and patients therefore often respond very differently to the drugs they receive. Cancer precision medicine aims to characterise the tumour (and often also the patient) to be able to predict, with high accuracy, its response...

... to in the content or advertisements. Biorepository Genetics Qualitative focus Precision medicine Biobank Cancer Return of results Ethics National Institutes of Health (NIH) 10.13039/100000002 Collecting and storingtissue and genetic data in large repositories represents a powerful...

...Simon J. Hollingsworth; Andrew V. Biankin The drivers of precision medicine are clear: for patients (and physicians) - more options, durable clinical benefit, reduced exposure to non-effective drugs and potential to leverage current scientific and technological advances; for the pharmaceutical...