... will be needed. The European Alliance for Personalised Medicine (EAPM) has listed its own priorities: data, integrating innovation into care, building trust, developing skills and constructing policy frameworks that guarantee infrastructure, equitable access, and legal clarity. Artificial intelligence Big...

...Denis Horgan; Jonathan A. Lal Personalised medicine promises to revolutionise healthcare, with its key goal of providing the right treatment to the right patient at the right time, and thus the potential of improving quality of life and helping to bring down healthcare costs. However, a major...

... Personalised medicine Precision medicine Precision medicine first Tumour heterogeneity Molecular characterisation Next-generation sequencing Drug response Advances in next-generation sequencing (NGS) technologies are providing opportunities for genomic precision medicine and the promise...

...Kym M. Rae; Steve Grimson; Kirsty G. Pringle Personalised medicine is a newly emerging field with much to offer to all populations in improved clinical treatment options. Since the 1970s, clinicians and researchers have all been working towards improving the health of Indigenous Australians...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Personalised medicine Reimbursement challenges Sustainable health systems Value of diagnostic information In vitro diagnostics Companion diagnostics Diagnostic tests...

... that would contribute to what is called personalised medicine. In this paper, we will highlight the ethical issues surrounding rationalisation and its impact on personalised medicine through the lens of the capability approach. Thereby, challenges to and opportunities for personalised medicine...

...Juliette Plun-Favreau; Kaisa Immonen-Charalambous; Lotte Steuten; Anja Strootker; Roman Rouzier; Denis Horgan; Mark Lawler Molecular diagnostics can offer important benefits to patients and are a key enabler of the integration of personalised medicine into health care systems. However, despite...

...Sabine Tejpar; Roberto Salgado; on behalf of the Working Groups ‘Biomarker'' and ‘Clinical Trial Framework'' of the European Alliance for Personalised Medicine (EAPM) The convergence of new biological insights from sequencing, digital technologies and advanced bioinformatics tools are creating new...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Validation Clinical utility Policy Regulatory requirements Personalised medicine Companion diagnostic Biomarkers...

... to in the content or advertisements. Targeted drugs Healthcare systems Precision medicine Oncology Drug development Personalised medicine Stratified medicine We live in an era promising (routine) delivery of precision medicine, driven by rapid and substantial developments in the understanding...

... modelling In silico clinical trials Virtual patient Mechanistic models Personalised medicine Despite significant progress in the quality of services offered by health care systems over the last decades, leading to drastic improvements in health and well-being of the general public, our health...

...Denis Horgan; Marleen Jansen; Lada Leyens; Jonathan A. Lal; Ralf Sudbrak; Erica Hackenitz; Ulrike Bußhoff; Wolfgang Ballensiefen; Angela Brand Background: Personalised medicine (PM) is an innovative way to produce better patient outcomes by using an individualised or stratified approach to disease...

... Genomics Health policy Personalised medicine Public health Translation Public health genomics has almost reached the age of 15. It started in 1997, the year the Office of Public Health Genomics was established at the Centers for Disease Control and Prevention in the USA; and entirely...