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Keywords: UDP-glucuronosyltransferase 1A6
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Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (2009) 84 (4): 219–226.
Published Online: 10 September 2009
...Jianteng Gu; Kaizhi Lu; Peiyuan Xia; Min Tang; Qing Dai; Daqing Ma; Guocai Tao Objective: The metabolic enzyme of UDP-glucuronosyltransferase 1A6 (UGT1A6) has been considered to metabolize propofol intra- or extrahepatically. The aim of the present study was to investigate the pharmacokinetics...
Journal Articles
Subject Area:
Pharmacology
Martijn G.H. van Oijen, Christine Barthélémy, Marcel J.R. Janssen, Etienne Joiris, Wilbert H.M. Peters, Robert J.F. Laheij, Paul Smits, Pascal Odou, Jan B.M.J. Jansen
Journal:
Pharmacology
Pharmacology (2009) 83 (4): 237–242.
Published Online: 05 March 2009
... in the gene encoding for UDP-glucuronosyltransferase 1A6 (UGT1A6), an enzyme involved in ASA metabolism. Methods: Five UGT1A6 * 1 and 4 UGT1A6 * 2 homozygote females were given 320 mg ASA once daily for 8 days. During the first and last day of treatment, several blood samples were taken over a 10-hour time...
