... ileum, urinary bladder and trachea (a) confirms the presence of such components of effect (ileum and bladder); (b) indicates TRPV1 involvement in the effect of 5 or 30 µmol/l of P on the basis of an inhibitory action of the antagonist BCTC (ileum); (c) indicates that HC 030031-sensitive TRPA1 receptors...

...)-induced mucus production. Methods: Tracheas from donor rats were homografted to recipient rats for 4 weeks, and the usefulness of this tracheal homograft model in the study of mucus production was examined. Results: Oral administration of clarithromycin (CAM) to recipient rats for 4 weeks significantly...

...Yu Huang; C.-W. Lau The effects of amitriptyline, a tricyclic antidepressant, on contractile responses to exogenously applied acetylcholine, endothelin 1 and high K + were examined in the rat isolated trachea. Amitriptyline (0.3–30 µmol/l) produced a shift to the right of the logarithmic...

...Penelope A. Hutson; J.R. Carpenter When guinea pig isolated trachea is contracted with either carbachol or methacholine, relaxant concentration-response curves to isoprenaline, salmefamol and fenoterol were shifted to the right, compared with curves obtained with either spontaneous or histamine...

.... Diabetes mellitus, experimental Trachea Phosphodiesterase inhibitors 7 1 2000 Short Communication Pharmacology 2000;60:9 12 Received: March 5, 1999 Accepted after revision: May 31, 1999 Comparison of the Effects of Selective III, IV and Nonselective Phosphodiesterase Inhibitors on Isolated...