... receptors. Intraplantar administration of the specific M 1 receptor antagonist telenzepine (TEL; 6, 12 and 24 µg/paw) caused a dose-dependent reduction in the nociceptive threshold induced by Cg (125 µg/paw). This effect was not observed with increasing doses (4, 10 and 40 µg) of other specific receptor...

...Reinhold W. Stockbrügger The M 1 -selective antimuscarinic drugs pirenzepine and telenzepine moderately reduce gastric acid secretion without inhibiting smooth-muscle activity as much as nonselective antimuscarinics, e.g. atropine and 1-hyoscyamine. They hasten peptic ulcer healing and improve...

...Catherine B. Chan; Andrew H. Soll Stimulation of acid secretion by muscarinic agents involves receptors with a higher apparent affinity to the M1-antagonists, pirenzepine and telenzepine, than those regulating heart rate and salivary secretion. However, the localization of the proposed M1-receptors...

...C. Schudt; C. Auriga; N.J.M. Birdsall; R. Boer The affinities of telenzepine, pirenzepine and atropine for muscarinic acetylcholine receptors have been determined by receptor binding studies using brain cortex and heart membranes of calf and rat. The ratios of affinities of telenzepine...

...W. Kromer; S. Gönne In the rat, the antiulcer potencies of the M 1 antimuscarinics telenzepine and pirenzepine, the H 2 receptor blocker cimetidine, and the H + /K + -ATPase inhibitor omeprazole were compared with their antisecretory potencies. On a molar basis and with regard to inhibition...

...) and antagonized by the Ml receptor antagonist pirenzepine (100 nmol/l) and telenzepine (100 nmol/l), but not by the M2 receptor antagonist AF-DX 116 (1 μmol/l). Slow excitatory postsynaptic potentials recorded from curarized rabbit isolated superior cervical ganglia were also blocked by telenzepine (300 nmol/l...

... and himbacine against McN-A-343 and carbachol was similar. However, pirenzepine and telenzepine displayed preferential antagonism of McN-A-343 responses, whereas the converse was true for methoctramine and AF-DX 116. The pA 2 values of 6 antagonists against carbachol responses in rabbit vas deferens closely...