...Sónia A. Silva; Carlos A. Fontes Ribeiro The in vitro contractile response of the human uterine artery to sumatriptan was compared to that of human cerebral blood vessels. Artery rings were prepared for isometric contraction. Tachyphylaxis to the triptan-induced vascular contraction was observed...

...Guglielmina Froldi; Monica Montopoli; Miriam Zanetti; Paola Dorigo; Laura Caparrotta The effects of 5-hydroxytryptamine (5-HT), 5-carboxamidotryptamine, and sumatriptan on rat caudal arteries were examined, with the goal of finding experimental conditions useful in enhancing the ‘silent’ 5-HT 1B...