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Keywords: Subthreshold method
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Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (2008) 81 (3): 259–265.
Published Online: 04 February 2008
... electroshock seizure test in mice and its ED 50 value was 13.71 (11.95–15.73) mg/kg. In the subthreshold method, MRZ 2/576 (administered intraperitoneally, at a subthreshold dose of 5 mg/kg) significantly enhanced the anticonvulsant action of felbamate, oxcarbazepine and topiramate, by reducing their ED 50...