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Keywords: Substance P
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Journal Articles
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2011) 87 (3-4): 152–154.
Published Online: 22 February 2011
...Masahisa Shindo; Yuichi Yoshida; Osamu Yamamoto Capsaicin, a vanilloid, has the potential for releasing substance P (SP) from sensory nerves. Topical application of capsaicin induces a flare response in the skin. However, it has not been clarified whether the release of SP is involved...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2010) 85 (1): 36–40.
Published Online: 16 December 2009
... of the biting behavior induced by intrathecal injection (i.t.) of glutamate (175 nmol/site), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA; 135 pmol/site), (±)-1-aminocyclopentane- trans -1,3-dicarboxylic acid ( trans -ACPD; 50 nmol/site) and substance P (SP, 135 ng/site). Tramadol injected...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1989) 38 (1): 1–15.
Published Online: 05 June 2008
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Substance P Neurokinin A Neurokinin B Smooth muscles Receptor Selective agonists Mono-multireceptor systems Current...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1990) 41 (4): 184–194.
Published Online: 05 June 2008
... described in this paper provide important tools for pharmacological studies on NK. Substance P Neurokinins Smooth muscle Antagonists Neurokinin-2 receptor Pharmacology 1990;41:184-194 © 1990 S. Karger AG, Basel 0031 -7012/90/0414-0184S2.75/0 Structure-Activity Study of Neurokinins: Antagonists...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1990) 41 (3): 119–123.
Published Online: 05 June 2008
... generated much greater tension in response to ATP, serotonin, histamine, and substance P. The response of the 1-day-old bladder smooth muscle to these contractile agents was at least double the response of the 8-week-old bladders. However, the response of all age groups to bethanechol was approximately...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1982) 25 (1): 39–50.
Published Online: 04 June 2008
...J. Mizrahi; R. Couture; S. Caranikas; D. Regoli Peptide and non-peptide agents were tested for their stimulatory or inhibitory effects on circular strips of guinea pig isolated tracheae. Substance P, eledoisin, physalaemin, neurotensin, angiotensin, histamine and carbachol were found to contract...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1986) 33 (5): 266–273.
Published Online: 04 June 2008
...M. Roch-Arveiller; D. Regoli; B. Chanaud; M. Lenoir; O. Muntaner; S. Stralzko; J.-P. Giroud Chemotactic and chemoluminescent activities of substance P, substance K, kassinin and the substance P fragments SP 4-11, SP 7-11, SP 1-4 have been investigated in order to identify the minimum active...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1982) 25 (6): 320–326.
Published Online: 04 June 2008
...J. Mizrahi; P. D’Orléans-Juste; S. Caranikas; D. Regoli Stimulants (histamine, acetylcholine and substance P) and relaxants (isoprenaline and bradykinin) of the guinea pig trachea were tested in the absence and presence of mepacrine, eicosatetraynoic acid, BW 755C and indomethacin in order...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1983) 27 (6): 305–318.
Published Online: 04 June 2008
...D. Mastrangelo; R. Mathison; H. Huggel A dose-dependent contractile effect of substance P (SP) on the isolated, everted rat portal vein was competitively inhibited by two selective SP antagonists (pro 2 , phe 7 , trp 9 )-SP and (pro 4 , trp 7,9 )-SP 4–11. Phentolamine, atropine, methysergide...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1984) 28 (6): 301–320.
Published Online: 04 June 2008
...D. Regoli; E. Escher; J. Mizrahi Various attempts to developing antagonists for substance P (SP) and related peptides, based on our past experience with angiotensin, kinins, and neurotensin, were unsuccessful. The particular features of SP, namely the high activity of C-terminal partial sequences...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1982) 24 (1): 1–25.
Published Online: 30 May 2008
...R. Couture; D. Regoli Substance P (SP), some of its C-terminal fragments and some of its homologues (physalaemin and eledoisin) are hypotensive in rats anaesthetised with urethane, vasodilators in isolated rabbit hearts, inhibitors of noradrenaline-induced contractions of the dog carotid artery...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1982) 24 (4): 230–242.
Published Online: 30 May 2008
...R. Couture; J. Mizrahi; S. Caranikas; D. Regoli Stimulatory or inhibitory effects of a number of peptides were measured on the longitudinal strip of the rat-isolated colon. Substance P, neurotensin, bombesin, enkephalins, dynorphin, angiotensin, somatostatin, eledoisin and physalemin-induced...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2003) 69 (2): 93–101.
Published Online: 03 September 2003
... the mechanism by which methysergide inhibited the nociceptive behaviors induced by formalin, the antinociceptive effect of methysergide was also tested in substance P (i.t.) and excitatory amino acids (i.t.), such as glutamate, N-methyl- D- aspartic acid, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2002) 65 (2): 83–86.
Published Online: 03 May 2002
...Leda Gaspani; Elena Limiroli; Paolo Ferrario; Mauro Bianchi The effects of bromelain were examined in rats with subcutaneous carrageenin-induced inflammation. After oral in vivo administration, bromelain (10 and 20 mg/kg p.o.) induced a significant decrease of both PGE 2 and substance P...