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1-20 of 23
Keywords: Spontaneously hypertensive rats
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Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (2018) 101 (3-4): 120–132.
Published Online: 30 November 2017
... 6c and angiotensin II after stroke by inducing transient middle cerebral artery occlusion in spontaneously hypertensive rats and Wistar-Kyoto rats using the wire-myograph. We demonstrated an increased contractile response to endothelin 1 and extracellular potassium as well as an increased carbachol...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (2011) 87 (5-6): 257–264.
Published Online: 14 April 2011
..., to regulate blood pressure in spontaneously hypertensive rats (SHRs) and examined the mechanism(s) by which loperamide exerts its effects. Methods: In male SHRs, mean arterial pressure (MAP) was measured and hemodynamic analysis was recorded. Additionally, the isometric tension of aortic rings isolated from...
Journal Articles
Subject Area:
Pharmacology
Ike Campomayor dela Peña, Seo Young Yoon, Sung Mok Kim, Geum Seon Lee, Jong Hoon Ryu, Chul-Seung Park, Yong Chul Kim, Jae Hoon Cheong
Journal:
Pharmacology
Pharmacology (2009) 83 (6): 367–378.
Published Online: 18 May 2009
... pressure and heart rate). When tested in the spontaneously hypertensive rats (SHR) for its influence on their voiding behavior, LDD175 (5 and 10 mg/kg) significantly reduced voiding frequency and lengthened void intervals of the animals. These observations: (1) reveal the BKCa channel potentiation...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1995) 51 (2): 96–104.
Published Online: 10 June 2008
... to in the content or advertisements. Wistar-Kyoto rats Spontaneously hypertensive rats Hypertension Radioimmunoassay Ontogeny Central nervous system Heart Aorta Original Paper Pharmacology 1995;51:96-104 Ravi S. Iyerb Govind Singh* Sam Rebelloa Sujoy Roy3 Rama Bhatb Dharmapuri Vidyasagarb Anil...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1995) 50 (4): 261–265.
Published Online: 10 June 2008
...C.H. Cho; S.K. Kaon; H.H. Wang It has been reported that there are functional defects in the purinergic system in spontaneously hypertensive rats (SHR). The following experiments examined the gastric effects of adenosine in these animals. SHR had a significantly higher gastric mucosal blood flow...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1995) 50 (1): 40–50.
Published Online: 10 June 2008
...So C. Wong; Alphonse J. Ingenito To determine whether the peripheral opioid system participates in hypertension development we studied responses to various opioid receptor agonists in field-stimulated isolated tail artery segments taken from spontaneously hypertensive rats (SHR), normotensive...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1992) 44 (1): 19–25.
Published Online: 06 June 2008
..., Gainesville, Fla.. USA 3H-IMorepinephrine Release in Caudal Artery of Spontaneously Hypertensive and W istar-Kyoto Rats: Effects of Altered Salt Diets Keywords Spontaneously hypertensive rats 3H-norepinephrine release Caudal artery Low sodium High sodium Abstract The potassium-induced release of 3H...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1993) 46 (2): 75–81.
Published Online: 06 June 2008
...-Pen 5 -enkephalin Brain regions Spinal cord Spontaneously hypertensive rats Wistar-Kyoto rats © 1993 S. Karger AG, Basel 1993 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1992) 45 (1): 52–57.
Published Online: 06 June 2008
... at any age. These results suggest that hippocampal receptor changes involving the opioid system may play a role in the central component of blood pressure control. 30 08 1991 2 12 1991 6 6 2008 Kappa-receptor Spontaneously hypertensive rats Opiate Dynorphin [ 3 H]-etorphine...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1992) 45 (1): 34–40.
Published Online: 06 June 2008
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Spontaneously hypertensive rats Kaliuresis Early distal tubular diuretics Defect of potassium transport Distal nephron Amiloride 19 08 1991 1 11 1991 6...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1990) 41 (2): 67–74.
Published Online: 05 June 2008
... preparations of spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY). Supplementation in the drinking water with 0.5 or 1.0% KCl for 5 weeks lowered blood pressure (19 and 25 mm Hg, respectively) in SHR but had no effect on WKY. The decrease in blood pressure with 0.5% KCl was not accompanied...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1988) 36 (2): 101–105.
Published Online: 05 June 2008
... injected physostigmine. A similar reduction was obtained with l/80th the dose of methyl-atropine, but not with the selective Ml antagonist pirenzepine. Intra ventricular injection of 4-DAMP (6.25–25 μg) caused a dose-related reduction in blood pressure in unanesthetized spontaneously hypertensive rats (SHR...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1983) 27 (6): 319–324.
Published Online: 04 June 2008
...Ching-Long J. Sun; Joseph P. Hanig Spontaneously hypertensive rats (SHR) were compared to their controls, WistarKyoto (WKY) rats, with respect to contractile responses of aortic preparations and catecholamine concentrations in aorta and superior cervical ganglion (SCG). Contractile responses...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1969) 19 (3): 156–162.
Published Online: 29 May 2008
...Gene C. Palmer; Stan Greenberg Particulate fractions of myocardium taken from spontaneously hypertensive rats (SHR) contained an adenylate cyclase system that was less responsive than normotensive Wistar Kyoto rats to norepinephrine, isoproterenol (mixed β-agonist), salbutamol (β 2 -agonist), do...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1971) 5 (3): 153–164.
Published Online: 28 May 2008
... Words tent, norepinephrine retention, and the activity Systolic blood pressure of enzymes involved in the synthesis and de DOCA and NaCl hypertension gradation of catecholamines were examined in Spontaneously hypertensive rats several organs of inbred rats which developed Catecholamines hypertension...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (2004) 71 (2): 91–101.
Published Online: 05 May 2004
... pressure and heart rate in normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). The effects of eugenosedin-A-decreased blood pressure and heart rate in SHR were more potent than in WKY. In in vitro experiments, eugenosedin-A competitively antagonized the serotonin-, norepinephrine...
Journal Articles
Subject Area:
Pharmacology
Atsuo Tahara, Junko Tsukada, Yuichi Tomura, Koh-ichi Wada, Toshiyuki Kusayama, Noe Ishii, Takeyuki Yatsu, Wataru Uchida, Nobuaki Taniguchi, Akihiro Tanaka
Journal:
Pharmacology
Pharmacology (2003) 67 (2): 106–112.
Published Online: 13 January 2003
... in young spontaneously hypertensive rats (SHR) during the developmental phase of hypertension were compared with those of age-matched Wistar-Kyoto (WKY) rats using the radioligand receptor assay technique. The systolic blood pressure of 8-week-old SHR was statistically significantly higher than that of WKY...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (2002) 64 (4): 196–200.
Published Online: 06 March 2002
...Jagdish N. Sharma; Uma Kesavarao We investigated the total urinary kallikrein levels, left-ventricular wall thickness and mean arterial blood pressure of nontreated and captopril-treated diabetic and nondiabetic spontaneously hypertensive rats. The mean arterial blood pressure was significantly...
Journal Articles
Subject Area:
Pharmacology
Yuki Setoguchi, Toshio Ohnuki, Mamunur Rashid, Takashi Nakamura, Kaoru Hattori, Takafumi Nagatomo, Kenichi Watanabe, Akio Mitomi, Mikio Nakazawa
Journal:
Pharmacology
Pharmacology (2002) 64 (2): 71–75.
Published Online: 10 January 2002
...) and spontaneously hypertensive rats (SHRs) were studied and compared with those of quinapril (ACE-I). Sarpogrelate and quinapril were administered orally for 12 weeks and body and heart weights, systolic blood pressure and the relationships between heart weight and systolic blood pressure were determined. Although...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (2000) 60 (1): 47–50.
Published Online: 07 January 2000
...Oscar Fernández; Rosemary Wangensteen; Antonio Osuna; Félix Vargas This study was performed to determine the possible contribution of an imbalance between P 2X (vasoconstriction) and P 2Y (vasodilation)-purinergic reactivity to the increased vascular resistance of spontaneously hypertensive rats...
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