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Keywords: Spinal cord
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Journal Articles
Pharmacology (2020) 105 (3-4): 173–180.
Published Online: 02 October 2019
... examined in the spinal cord. Results: Intrathecally administered KRG produced a limited, but a dose-dependent, antiallodynic effect. Intrathecally administered DHE antagonized the antiallodynia caused by KRG. Furthermore, intrathecal SB269970 also reversed the effect of KRG. No changes in 5-HT 7 receptor...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2018) 102 (5-6): 332–338.
Published Online: 10 October 2018
...-adrenoceptors Spinal cord Neuropathic pain (NP) is caused by a lesion or disease affecting the somatosensory nervous system, which causes allodynia [ 1 ]. Despite the use of analgesics, no more than half of patients experience clinically meaningful pain relief [ 2 ]. In addition, recent studies have...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2014) 94 (1-2): 29–40.
Published Online: 28 August 2014
... and pituitary gland), GLUT-4 (muscle) and GLUT-3 (adrenal gland) expression levels were increased, whereas GLUT-1 (brain cortex, liver, muscle and spinal cord), GLUT-2 (liver) and GLUT-3 (brain cortex and pituitary gland) expression levels were decreased. Discussion: Our data suggest that PTX administered...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2010) 85 (5): 295–300.
Published Online: 05 May 2010
... withdrawal mechanical threshold of von Frey filament was used to measure the thermal hyperalgesia and tactile allodynia, respectively. Lumbar spinal cords of the rats isolated on the 5th day after the operation were prepared to measure the mRNA expression of T-type (Cav3.1, Cav3.2 and Cav3.3) calcium channel...
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Journal Articles
Subject Area:
Pharmacology
Pharmacology (1989) 39 (3): 145–153.
Published Online: 05 June 2008
...Anil Gulati; Poduri Ramarao; Hemendra N. Bhargava The effect of repeated administration of U-50,488H, a κ-opioid receptor agonist, on the development of tolerance to its analgesic effect and on the 5-HT 1 and 5-HT 2 receptors in the cerebral cortex and spinal cord of the rat were determined. Male...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1971) 6 (4): 209–215.
Published Online: 28 May 2008
.... Further, during a long-lasting superfusion of spinal cord 5-HIAA is released in relatively constant amounts into superfusate. Thus, it is concluded that 5-HIAA in the spinal fluid derives, at least partly, from metabolism of 5-HT in the spinal cord. 30 06 1971 28 5 2008 © 1971 S. Karger...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2006) 76 (3): 105–109.
Published Online: 22 February 2006
...Li-Hua Hang; Ti-Jun Dai; Yin-Ming Zeng The present study was designed to investigate the relationship between spinal cord N-methyl- D -aspartate (NMDA) receptors and the analgesic effects of emulsified halogenated anesthetics. After having established the mouse model of analgesia...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2005) 75 (3): 157–164.
Published Online: 14 October 2005
.... The authors assessed the characteristics of the interaction of the adenosine-excitatory amino acid antagonist combinations in the spinal cord of rats on the formalin-induced nociception. Intrathecal NMDA antagonist ((5R, 10S)-(+)-5-methyl-10,11-dihydro- 5 H-dibenzo[a[,]d]cyclohepten-5,10-imine hydrogen...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2005) 74 (3): 152–156.
Published Online: 02 June 2005
... that orally administered ASA and ACET produce antinociception by inhibiting the nociceptive action of TNF-α, IL-1β or IFN-γ administered intrathecally. 20 07 2004 25 01 2005 2 6 2005 Aspirin Acetaminophen TNF-α IL-1β or IFN-=γ Spinal cord © 2005 S. Karger AG, Basel 2005...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2001) 62 (3): 145–150.
Published Online: 30 March 2001
..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Analgesia, Spinal cord Dantrolene Thapsigargin Calcium, intracellular...