... have been published about the effects of hydroxycarbamide (hydroxyurea, HU) and anagrelide (ANA) on renal function in ET patients. This study is the largest analysis of nephrotoxicity of cytoreductive drugs used in ET therapy so far, which additionally includes risk factors for the progression...

.... A total of 128 plasma febuxostat concentrations from 26 patients were used in the population pharmacokinetic analysis. The data were best described by a 1-compartment model with first order absorption. Covariate analysis revealed that renal function did not influence the pharmacokinetics of febuxostat...

...Romain Nati; Michael Campean; Herbert J. Kramer It was previously shown in man that metoclopramide (MCP), a dopamine (DA)-2 receptor blocker, attenuates the natriuresis of water immersion. In the present study, we therefore investigated the effects of MCP on renal function and atrial natriuretic...

...Larry A. Walker; James N. Rider; Alan B. Jones This study evaluated the changes in renal function that occur during the early phases of chronic infusion of carbachol into the lateral ventricle in conscious rats. Infusion of 1.0 µg/h of carbachol i.c.v. resulted in a prompt pressor response...

...Rose M. Threatte; Melvin J. Fregly; Peter Field Renal hypertension in rats was accompanied by both a decrease in thyroid activity (i.e., decreased total serum triiodothyronine concentration, increased serum thyroid-stimulating hormone concentration and increased thyroid weight) and renal function...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fasidotrilat Angiotensin I-converting enzyme Neutral endopeptidase Heart failure Renal function Original Paper Pharmacology 1998;56:291 296 Received: July 30, 1997 Accepted...