...Francesca Mori; Simona Barni; Lisa Pecorari; Lucrezia Sarti; Neri Pucci; Elio Novembre Although reversible H2 receptor antagonists are usually well tolerated, there are few reports on anaphylactic reactions triggered by ranitidine. Here we report the first case of anaphylaxis to ranitidine...

...S.L. Grainger; M.N. Nanjee; R.P.H. Thompson; N.E. Miller The effects of cimetidine (400 mg b.d.) and ranitidine (150 mg b.d.) on high-density lipoprotein (HDL) subclasses and other plasma lipoproteins were studied in 18 men and 15 women with reflux oesophagitis and/or duodenitis. Serum testosterone...

...Lamberto Re; Bernardino Di Sarra The effects of some histamine H 2 -receptor antagonists on the cholinergic system have been evaluated at the mouse end-plate. Previous data revealed interactions at both pre- and post-synaptic sites for cimetidine and ranitidine. The present work shows the effects...

... enhanced incorporation of the tracers into cellular and released AIM in a concentration-dependent manner. The H 2 receptor antagonist ranitidine completely blocked the effects of histamine (100 μmol/l) on [ 3 H]Leu incorporation into cellular and released AIM (IC50 37 and 32 μmol/l, respectively) but had...

...K.-F. Sewing; H. Hannemann The inhibitory effects of the histamine H 2 -receptor antagonists, ranitidine and famotidine on histamine-stimulated gastric acid secretion have been studied in guinea pig isolated, enriched parietal cells using the 14 C-aminopyrine accumulation technique. The 14 C...

...G. Perret; J.N. Hugues; M. Louchahi; O. Varoquaux; E. Modigliani Cimetidine (400 mg b.d.), ranitidine (150 mg b.d.) and placebo were administered for 1 week to 6 healthy male volunteers in a randomized double-blind cross-over fashion. Hormonal concentrations before and after a TRH test were...

...Dyal C. Garg; Neyton Baltodano; Guido O. Perez; James R. Oster; Nader S. Jallad; Donald J. Weidler The pharmacokinetics of ranitidine and its removal by hemodialysis were determined in 9 patients with chronic renal failure requiring hemodialysis. Ranitidine (50 mg) was administered...

... pyrilamine (40 µg/mouse) and the histamine H2 receptor antagonist ranitidine (6.25 and 12.5 µg/mouse) prevented the improving effect of pre-test lithium (10 mg/kg i.p.) on memory retrieval. The results suggest that the repeated administration of histaminergic agents may induce a sensitization which affects...

...Full-Young Chang; Tseng-Shing Chen; Shou-Dong Lee; Guey-Hwa Yeh; Ming-Luen Doong; Paulus S. Wang The pharmacological potency of ranitidine to inhibit pentagastrin-stimulated gastric acid outputs was studied in early diabetic rats. Diabetes was induced by intravenous injection of streptozotocin 4...

... duration of action of a few hours. Ranitidine at the same oral dose also shows a short duration of action, but combined with a far lower efficacy. By contrast, a single oral dose of the PPI omeprazole elevates intragastric pH for a longer time period, but this pH elevation is far lower compared...