...Yanni Fang; Wenwen Jin; Zhen Guo; Jumei Hao Introduction: The aim of the study was to discuss whether the anti-asthmatic effect of quercetin is related to periostin and the downstream molecular pathway of quercetin’s anti-asthmatic effect. Methods: We constructed asthmatic mice, sensitized...

... by considerable side effects, high costs, and some limitations for patients. Thus, using an alternative way is needed. Summary: Presently, natural compounds based-therapies, like flavonoids, have acquired much attention in the current era. One of the compounds belonging to the flavonoid family is quercetin...

...Ju-Yong Song; Do Vinh Truong; Beom-Seok Yang Aim: Previous studies have suggested that quercetin is effective for treating diverse chronic disorders including organ fibrosis and airway and cardiovascular disorders. To access the pharmacological background for its broad efficacy, we examined...

... (AMs), one of the first lines of defense in the lung, are abundantly located in alveoli and the respiratory tract. Flavonoids found in fruits and vegetables exhibit cytoprotective effects on various cell types. In this study, we investigated the effect of quercetin on activation of AMs that had been...

...Hyun Soo Kwak; Sun Young Park; Thao Thanh Nguyen; Chung Hyo Kim; Jong Mi Lee; Jung Sook Suh; Wan Kyunn Whang; Uy Dong Sohn Background/Aims: In this study, we investigated the gastroprotective effect of extract including quercetin-3-O-β- d -glucuronopyranoside (EIQ) from Rumex aquaticus herba...

...Peng-Gao Li; Li Sun; Xin Han; Shuang Ling; Wo-ting Gan; Jin-Wen Xu Consumption of the flavonoid quercetin exerts beneficial effects on many chronic diseases. The mechanisms involved in the vasorelaxant effect of quercetin remain uncertain. In the present study, we examined the role of quercetin...

...Alarcón de la Lastra; M.J. Martín; V. Motilva This study was designed to determine the cytoprotective properties of quercetin and the involvement of endogenous prostaglandins in mucosal injury produced by absolute ethanol. Gastric glands were also analyzed histologically. Oral pretreatment...

... in myoglobinuric renal failure. This study was performed to explore the protective effect of quercetin, a bioflavonoid, in an experimental model of myoglobinuric ARF in rats. Four groups of rats were employed in this study: group 1 served as control, group 2 was given 50% glycerol (8 ml/kg, i.m.), group 3...

... blood vessels. We also found that quercetin, a common polyphenolic compound in foods of plant origin, induces HO-1 expression in RAW264.7 cells. This study was aimed at examining the potency of quercetin as a HO-1 inducer and its regulation in rat aortic smooth muscle cells (RASMCs). We showed...

... is still obscure. It may be caused by a loss of dopaminergic cells or may be due to free radicals as a product of high synaptic dopamine levels. Quercetin is a bioflavonoid with strong antioxidant properties. Repeated treatment with reserpine (1.0 mg/kg) on each other day for a period of 5 days (days 1, 3...

...Kamel Gharzouli; Peter Holzer Flavonoids are known to relax precontracted intestinal smooth muscle and to delay intestinal transit. We therefore investigated the effects of quercetin, naringenin, apigenin and genistein on intestinal peristalsis in vitro. Peristalsis in fluid-perfused segments...

... of success. Quercetin, a flavonoid present in many plants, is reported to inhibit COMT and MAO activities, the key enzymes involved in the metabolism of dopamine. In the present study we have studied the effect of quercetin on the L -dopa plus carbidopa combination against perphenazine and reserpine-induced...

... followed by reperfusion were tested and were further compared with those of quercetin and gallic acid, major antioxidative components of P. guajava L. and L. wrightii , respectively. Both extracts significantly attenuated ischemic contracture during ischemia and improved myocardial dysfunction after...

...L.P.N. Häckl; G. Cuttle; S. Sanches Dovichi; M.T. Lima-Landman; M. Nicolau Quercetin, one of the most widely distributed flavonoids in the plant kingdom, inhibits various enzymes. This study examined its inhibitory effect on the angiotensin-converting enzyme activity through the cardiovascular...