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Tomoyoshi Miyamoto, Yoshinori Funakami, Erika Kawashita, Shiori Tomita, Ai Nomura, Nanako Sugimoto, Haruka Saeki, Takaya Miyazakia, Maho Tsubota, Seiji Ichida, Atsufumi Kawabata
Pharmacology (2017) 99 (3-4): 172–178.
Published Online: 04 January 2017
... lipopolysaccharide Prostaglandin Stress Fever Hyperthermia Fever is one of the most common physiological responses to infection and systemic inflammation. Hyperthermia prevents the propagation of infectious microorganisms by activating the host's immune system [ 1 ]. Prostaglandin E 2 (PGE 2 ) produced...
Aline C.O. Costa, Lenice K. Becker, Éder R. Moraes, Thiago R.L. Romero, Luciana Guzzo, Robson A.S. Santos, Igor D.G. Duarte
Pharmacology (2012) 89 (3-4): 137–144.
Published Online: 12 March 2012
... test. For this test, sensitivity is increased by intraplantar injection of prostaglandin E 2 . Ang-(1–7) administered locally into the right hind paw elicited a dose-dependent antinociceptive effect. Because the higher dose of Ang-(1–7) did not produce an effect when injected into the contralateral paw...
Pharmacology (1992) 44 (6): 344–348.
Published Online: 06 June 2008
... 4 h after injection in rats fed a standard diet. However, IL-1 failed to inhibit serum IRI levels in rats fed a diet containing 1% probucol. In contrast, IL-1 decreased plasma glucose levels in both groups. Although IL-1 reduced plasma prostaglandin (PG) E 2 levels in standard diet-fed rats, IL-1...
Pharmacology (2001) 63 (1): 28–33.
Published Online: 28 May 2008
... Tadahiko Yamamoto N. Rani Kakar Ernest R. Vina Paul E. Johnson Richard J. Bing Huntington Medical Research Institutes, Department of Experimental Cardiology, Pasadena, Calif., USA Key Words Prostaglandin W Nitric oxide W Cyclooxygenase-2 W Aspirin W Celecoxib W NCX-4016 W Myocardial infarction Abstract...
Mina Yamamoto, Takayo Haruna, Kinichi Imura, Ichiro Hikita, Yoko Furue, Kenichi Higashino, Yoshinari Gahara, Masashi Deguchi, Kiyoshi Yasui, Akinori Arimura
Pharmacology (2008) 81 (4): 301–311.
Published Online: 21 February 2008
... in the biosynthesis of eicosanoids such as prostaglandins and leukotrienes. To examine the contribution of cPLA 2 α to skin inflammation, we evaluated the effect of (E)-N-[(2S,4R)-4-[N-(biphenyl-2-ylmethyl)-N-2-methylpropylamino]-1-[2-(2,4-difluorobenzoyl)benzoyl]pyrrolidin- 2-yl]methyl-3-[4-(2,4-dioxothiazolidin-5...
Hikaru Tanaka, Kazuhide Nishimaru, Ryuji Makuta, Wataru Hirayama, Taro Kawamura, Tomoyuki Matsuda, Yoshio Tanaka, Toru Kawanishi, Koki Shigenobu
Pharmacology (2003) 67 (3): 157–162.
Published Online: 17 February 2003
...Hikaru Tanaka; Kazuhide Nishimaru; Ryuji Makuta; Wataru Hirayama; Taro Kawamura; Tomoyuki Matsuda; Yoshio Tanaka; Toru Kawanishi; Koki Shigenobu The inotropic action of prostaglandins PGF 2α , PGD 2 and PGE 2 on isolated mouse left atria was characterized and compared with the positive inotropic...
Pharmacology (2001) 63 (4): 234–239.
Published Online: 06 December 2001
... interaction between ketoprofen and caffeine on prostaglandin (PG) biosynthesis and cyclooxygenase (COX) mRNA expression in the rat renal medulla ex vivo. Treatment of rats with ketoprofen (60 min before) resulted in a dose-dependent (estimated ID 50 0.3 mg/kg p.o.) reduction of PGE 2 biosynthesis in renal...
Pharmacology (2000) 61 (3): 154–166.
Published Online: 13 September 2000
... genes W Oxidative stress W Chemical carcinogen W Prostaglandin W Leukotriene W Basal cell carcinoma W Tissue-specific expression Abstract Two supergene families encode proteins with glutathione S-transferase (GST) activity: the family of soluble enzymes comprises at least 16 genes; the separate family...
Pharmacology (1999) 58 (5): 265–269.
Published Online: 08 April 1999
.... Gastric emptying Gastric inhibitory polypeptide Gastrointestinal motility Misoprostol Prostaglandin Original Paper Pharmacology 1999;58:265 269 Received: June 8, 1998 Accepted: November 14, 1998 Misoprostol-Inhibited Rat Gastric Emptying Is Independent of Gastric Inhibitory Polypeptide Release Full...