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Keywords: Propranolol disposition
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Journal Articles

The Disposition of Propranolol: II. Hepatic Elimination in the Rat

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Subject Area:
Pharmacology
D.G. Shand, R.E Rangno, G.H. Evans
Journal: Pharmacology
Pharmacology (1972) 8 (4-6): 344–352.
https://doi.org/10.1159/000136352
Published Online: 28 May 2008
... extraction falls. These findings explain the differences in propranolol disposition according to the route of administration. 30 08 1972 28 5 2008 © 1972 S. Karger AG, Basel 1972 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...
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Journal Articles

The Disposition of Propranolol: I. Elimination during Oral Absorption in Man

Available to Purchase
Subject Area:
Pharmacology
D.G. Shand, R.E. Rangno
Journal: Pharmacology
Pharmacology (1972) 7 (3): 159–168.
https://doi.org/10.1159/000136285
Published Online: 28 May 2008
... giving fully effective blood levels, results in a difference in propranolol disposition according to the route of administration. In addition, the presence of the apparent threshold for orally administered drug and the fact that propranolol probably reduces liver blood flow result in a lower estimate...
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