...Alfredo Costa; Daniele Bosone; Matteo Cotta Ramusino; Giulia Perini; Natascia Ghiotto; Annalisa Zoppi; Angela D'Angelo; Roberto Fogari Aim: To assess the effects of chronic evening oral administration of bromazepam alone or in combination with propranolol on ambulatory blood pressure (BP) and heart...

...Li Wei; Li Li; Bin Zhang; Lin Ma Background/Aims: To investigate the effect of propranolol on cobalt chloride (CoCl 2 )-induced hypoxic proliferation in human umbilical vein endothelial cells (HUVECs). Methods: CoCl 2 was administrated to HUVECs to mimic hypoxic proliferation in infantile...

...Patrizia Salice; Mario Giovanni Bianchetti; Alessandra Giavarini; Erica Gondoni; Riccardo Cavalli; Anna Maria Colli; Federico Lombardi Propranolol is becoming the treatment of choice for complicated infantile hemangioma. We report here data on peripheral blood flow, O 2 -saturation...

...Nobumitsu Hanioka; Keiko Hayashi; Takeshi Shimizudani; Kenjiro Nagaoka; Akiko Koeda; Shinsaku Naito; Shizuo Narimatsu The stereoselective glucuronidation of propranolol (PL) in human and cynomolgus monkey liver microsomes, and the roles of human hepatic UDP-glucuronosyltransferase (UGT) isofoms...

...Yi-Tsau Huang; Tsun-Bin Liu; Han-Chieh Lin; May Yang; Chuang-Ye Hong The purpose of this study was to investigate the therapeutic effects of tetrandrine and propranolol, alone or in combination, on portal hypertensive rats. Portal hypertension was induced by partial portal vein ligation in Sprague...

... of morphine and impaired memory retention. Propranolol 0.3 mg kg –1 along with morphine 3 mg kg –1 impaired memory retention only while haloperidol 0.1 mg kg –1 improved the impairment of memory retrieval caused by morphine 3 mg kg –1 . Glucose did not alter the effects of morphine on memory. There was no per...

...) but increased the heart rate (HR) accompanied by prolonged R-R (RR) or P-P interval (PP) (2) propranolol decreased SYa, DNa, dp, mp, HR, the amplitude of the P wave (Pa) and amplitude of the S wave (Sa) but increased the duration of the QRS wave, P-R interval, duration of the R wave (Rd) and duration of the P...

... neuronal uptake. The relative potencies of the three agonists were changed to NA ≥ NA, indicating the presence of beta-adrenoceptors. However, the shift of concentration-response curves by the beta-adrenoceptor antagonist propranolol varied according to the agonist used, suggesting the presence...

...B. Chindavijak; F.M. Belpaire; M.G. Bogaert A decrease of the hepatic intrinsic clearance could contribute to the increase of the plasma concentrations of α 1 -acid glycoprotein-bound drugs such as propranolol in animals and humans with inflammation. Therefore, the influence of inflammation upon...

... of verapamil required to reach the hemodynamic endpoint was 1,495 ± (SE) 165 µg/kg. In a second group, interactions between β-adrenergic blockade, propranolol 1 mg/kg (i.v.), and verapamil were examined. Although propranolol alone had only minor hemodynamic effects, the cardiac depressant dose of verapamil...

...John A. Barrett; Angela M. Magistro; Ronald D. Smith; Thaddeus P. Pruss; Peter S. Wolf Celiprolol, propranolol or saline were administered to separate groups (n = 5–6) of anesthetized dogs in which a critical stenosis was applied to the circumflex coronary artery for 90 min and then reperfused...

... (PAF), leukotriene D 4 (LTD4), compound 48/80 (48/80), and calcium ionophore A23187 (A23187). Propranolol overcame the inhibitory effect of isoproterenol on PCA and skin reactions in a dose-dependent manner. Theophylline and forskolin showed similar effects as the β-adrenergic stimulants. These results...

...E.F. Smith, III; J.W. Egan; D.E. Griswold This study was designed to assess the effect of propranolol for limiting myocardial damage and hypertrophy in rats with permanent coronary artery occlusion or occlusion followed by reperfusion. Rats were subjected to occlusion of the left main coronary...

...A. González-Gómez; D. Garcia-Barreto; R. Cabrera; A. Toruncha; A. Hernández-Cañero The effects of oral treatment with atenolol and propranolol on blood pressure, heart rate and plasma cyclic adenosine 3’:5’-monophosphate (cAMP) were studied in a group of young borderline hypertensives. Observations...

...Subbiah P. Sivam; Shiva Seth; Usha Nayar; Subash C. Manchanda The effect of intracerebroventricular (i.c.v.) ouabain alone and after pretreatment with i.c.v. (±)-propranolol, (+)-propranolol, UM-272 (a quaternary analogue of propranolol) and lignocaine, on arterial blood pressure (BP), heart rate...

...), propranolol (P), imipramine (IMP), and clomipramine (Cl-IMP) affected 5-HT disposition in rabbit lungs. Pulmonary ecxtraction and metabolism of [ 14 C]-5-HT during single pulmonary passage were examined using the reference indicator radioisotope dilution technique in male New Zealand albino rabbits. After...

... and reduced the coronary flow rate, but had no influence on the frequency and the oxygen consumption. The positive inotropic action of K-strophanthin and isoproterenol was slightly strengthened, whereas the β-adrenergic antagonism by propranolol and the vasodilatation by glycerol trinitrate remained unchanged...

...D. Cova; R. Colombo; G. Cellini A rapid and sensitive gas chromatographic method for the determination of the beta-adrenergic agent isoxsuprine in human plasma has been developed. The procedure involves the extraction of the drug with ether and an internal standard (propranolol) from plasma...

... in a concentration-dependent fashion. Propranolol (10 –6 M ) converted the norepinephrine-induced relaxations to contractions, and arotinolol (10 –6 –10 –5 M ) inhibited the relaxations induced by norepinephrine in a concentration-dependent manner. In proximal portions of the strips after potassium-contracture...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bepridil hydrochloride Diltiazem hydrochloride Verapamil hydrochloride Nifedipine Propranolol Lidocaine Cardiac...