...Ana Lasica; Cinzia Cortesi; Gregorio P. Milani; Mario G. Bianchetti; Federica M. Schera; Pietro Camozzi; Sebastiano A.G. Lava Introduction: Propofol occasionally induces a green or pink-cloudy urine discoloration. A lesser-known effect is green discoloration of hair, milk, liver, or stool. We aimed...

...JianE Wu; Fucheng Zhou; Shangshu Lai; Wenhua Wang; Ting Wu; Ying Liu; Li Yang Introduction: Hepatocellular carcinoma (HCC) is the most deadly cancer. Many signal pathways are implicated in HCC development, including sonic hedgehog (SHH). Propofol is an anesthetic commonly used in surgery. Recent...

...Chunling Wang; Shengnan Wang; Cuishuan Wu; Li Lei; Dong-Xin Wang; Qiang Zhang Introduction: The mixture of etomidate and propofol is widely used in clinical practice to improve efficacy of general anesthesia and to minimize side effects. As a thermodynamically unstable system, emulsion is prone...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Benzene GABA Phenol Propofol Selectivity National Institutes of Health (NIH) 10.13039/100000002...

...Wen-Zhe Jin; Jin-Di Shi; Heng Liu; Yan Lan; Chun-Ping Chu; De-Lai Qiu Propofol is a global central nervous system depressant that affects information processing in the central nervous system. However, the effects of propofol on sensory information processing in the cerebellar cortical molecular...

...Tingting Wang; Shengjin Ge; Wanxia Xiong; Peiwen Zhou; Jing Cang; Zhanggang Xue Background and Purpose: Stepwise propofol target-controlled infusion (TCI) can achieve a less disturbed condition of hemodynamics and respiration. Its combination with dexmedetomidine may have some advantages...

...Lijun Cao; Linyong Xu; Bosheng Huang; Lixiang Wu Background/Aims: Propofol, a widely used sedative-hypnotic agent for induction/maintenance of anesthesia and sedation of critically ill patients, reportedly has therapeutic potential for hypertension. Angiotensin-converting enzyme 2 (ACE2...

...Ye Tu; Tian Yu; Xiao-Yun Fu; Peng Xie; Sv Lu; Xiao-Qi Huang; Qi-Yong Gong Anesthesia, a state of profound central nervous system suppression, involves a sequence of events that is still not well understood. In the present study, we examined the action of propofol (a sedative-hypnotic drug commonly...

... administration of isoflurane, sevoflurane, or propofol on PKC-γ knockout mice and compared the times with those of wild-type mice. We also used immunoblotting to investigate the intracellular distribution of PKC-γ and phosphorylated PKC-γ (p-PKC-γ) in brain cell fractions obtained from wild-type mice during...

...Jianteng Gu; Kaizhi Lu; Peiyuan Xia; Min Tang; Qing Dai; Daqing Ma; Guocai Tao Objective: The metabolic enzyme of UDP-glucuronosyltransferase 1A6 (UGT1A6) has been considered to metabolize propofol intra- or extrahepatically. The aim of the present study was to investigate the pharmacokinetics...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Glycine receptor Volatile anaesthetics Propofol Comments Pharmacology 2008;81:195 DOI: 10.1159/000112943 Received...

...Yousuke Shiga; Kouichiro Minami; Yasuhito Uezono; Kayoko Segawa; Etsuko Nagaoka; Munehiro Shiraishi; Takashi Noguchi; Akio Shigematsu Intravenous anaesthetics such as ketamine, propofol, and thiamylal are widely used, although the direct effects of these anaesthetics on the renal blood flow (RBF...