...Esther Juarez Cortés; Gustavo López y López; Eduardo I. Perez Muñoz; Betzabel Rodriguez Reyes; Damian A. Madrigal-Aguilar; Rosa A. Bobadilla-Lugo Introduction: Obesity during pregnancy can contribute to hypertensive complications through changes in glucose utilization. We investigated the impact...

...Ji-Yin Zhou; Xiao-Huang Du; Zuo Zhang; Gui-Sheng Qian Background: As an active component from traditional Chinese medicine, trigonelline has a protective effect on diabetes. This study evaluated the protective effects of trigonelline on diabetic mice during pregnancy. Methods: Diabetes was induced...

...Pedro López-Sánchez; Ismael Bracho Valdés; Daniel Godínez-Hernández; Rosa A. Bobadilla-Lugo Vessels from pregnant animals show a blunted response to adrenergic agonists. In this work, we explored if pregnancy reduces α 1 -adrenergic receptor (α 1 -AR)-mediated vascular smooth muscle protein...

...Yat·Ching Tong; Ying-Cho Hung; Johnny S.N. Lin; Chao-Tien Hsu; Juei-Tang Cheng Previous studies have shown that pregnancy is associated with a decrease in cholinergic function in the rabbit urinary bladder. The present study aimed at evaluating the effects of pregnancy on the autonomic function...

... investigates the effects of pregnancy on the contractile responses of the isolated urinary bladder to cholinergic and purinergic stimulation. The results of these studies indicate that pregnancy induces substantial changes in the physiology and pharmacology of the urinary bladder. The following data...

...R. Garcia-Villar The effects of sennosides on uterine motility were evaluated by electromyography in healthy adult ewes between day 70 and 120 of pregnancy to assess possible disturbances of the physiological pattern of contractility and eventual risks in pregnancy maintenance. At this stage...

... and a more compliant fetal urinary tract. No one has investigated the possibility that such dilatations might be a consequence of the hormonal changes seen with pregnancy. In this study we present evidence for a change in bladder function with pregnancy. A summary of our results shows that in the presence...

...Richard L. Naeye Data from a large prospective study were analyzed to determine if taking dextroamphetamine during pregnancy affects fetal growth or fetal/neonatal mortality. 237/42,101 women took the drug to control weight gain. Birth weights were not significantly affected when the drug...

...P.V. Luoma; J.E. Heikkinen; P.R. Ylöstalo The effect of phenobarbital (PB) on serum hormones in late pregnancy was investigated. 18 pregnant women were studied before and after 2 weeks of PB treatment (100 mg per os, daily at 8 p.m.) by measuring serum estradiol, estriol, progesterone, testosterone...

...D.S. Sitar; A. Abu-Bakare; R.J. Gardiner Propylthiouracil (PTU) disposition was investigated in hyperthyroid women during pregnancy and post partum. The plasma half-life after the first dose averaged 0.66 h and became greater than 1 h with chronic drug therapy. The apparent volume of distribution...

...-treated females had lower body weights throughout pregnancy, but gained weight during lactation; by postnatal day 21, both groups were of comparable body weight. No significant differences in food consumption throughout gestation or lactation were recorded. Total water consumption of methadone-treated...

...Ian S. Zagon; Patricia J. McLaughlin The effect of chronic maternal morphine exposure on conception, pregnancy, and perinatal development was studied in rat. Beginning 5 days prior to mating and continuing through gestation and lactation, female Sprague-Dawley albino rats received twice daily...

...Sabrina F.S. Lisboa; Paulo E. Oliveira; Leandro C. Costa; Emerson J. Venâncio; Estefânia G. Moreira Background/Aims: Fluoxetine (FLX) has been widely prescribed for depression during pregnancy and/or lactation. Since serotonin is a neurotrophic factor, the use of FLX by mothers could disrupt brain...

...Janet I. Ejiofor; Helen O. Kwanashie; Joseph A. Anuka Artemether, highly effective in multi-drug-resistant malaria is not routinely available for use in pregnancy due to the lack of adequate research data in animals and man. This study was therefore aimed at investigating some pregnancy-related...