... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Sertraline Population pharmacokinetics Nonlinear mixed-effects modeling Creatinine clearance Dose adjustment...

... + 6.33 * CLcr. These findings suggest that the routine measuring of serum creatinine level may be used to facilitate administration of bisoprolol in patients on hemodialysis. Bisoprolol Hemodialysis Population pharmacokinetics Non-linear mixed-effects model [email protected] 24...

... hemodialysis) on the pharmacokinetics and therapeutic effects of febuxostat using a population pharmacokinetic analysis. This study recruited patients with hyperuricemia who were initially treated with allopurinol, but were switched to febuxostat, and it consists of 2 sub-studies: a pharmacokinetic study (26...

...Ling Xue; Hua Zhang; Sheng Ma; Jian-Zhong Rui; Li-Yan Miao Aim: The aim of this study was to establish population pharmacokinetic models of tacrolimus in healthy Chinese volunteers. Methods: A total of 956 tacrolimus whole blood concentrations from 73 healthy volunteers were determined using...