... decreased HR (accompanied by prolonged RR and PP) and Pa but increased Wd, Pd, SYa, DNa, Dw, dp, mp, Ra and Ta; (5) phenylephrine decreased HR (accompanied by prolonged RR and PP) and Pa but increased Wd, Dd, DNa, mp and Ra; (6) phentolamine decreased SYa, DNa, DWa, Dw, dp and mp. This study illustrates...

... shift the concentration-response curves to 5-HT. Phentolamine inhibited the 5-HT response (pA 2 = 6.69), and previous treatment of the vascular strips with 6-hydroxydopamine only partially reduced such an effect. The results demonstrate the existence, in the human uterine artery, of 5-HT 2 receptors...

... dependence also resulted in subsensitivity of the vas to the effects induced by α 2 -adrenoceptor agonist clonidine, the α-receptor antagonists phentolamine and phenoxybenzamine, as well as to adenosine and naloxone. These results indicate that the biochemical mechanisms of ethanol express themselves at both...

... (sCT) analgesia as measured in rats by the hot-plate test. Pretreatment with an α- and β-blocker (phentolamine and propranolol) was also effective in lowering significantly the activity of sCT. When the two drugs were administered alone, propranolol, but not phentolamine, reduced the analgesic effect...

...Edward E. Soltis; Michael J. Katovich Rat aortic smooth muscle responsiveness to potassium chloride and isoproterenol in the presence of the α-adrenergic blocker phentolamine was investigated. A significant decrease in the response of the vascular smooth muscle of aorta to low concentrations...

...Kenneth M. Hanson; Judith A. Post; Mary A. Desiderio The effects of α-adrenergic blockade with phentolamine or dibenamine on the cardiovascular response to pharmacological doses of vasopressin were studied in anesthetized dogs. Some observations were also made on the combined effects of vasopressin...

...-adrenergic receptors since they are blocked by propranolol. Propranolol pretreatment prevented the isoproterenol-induced decreases in renal clearances of methoxy-inulin and tetraethylammonium bromide. Treatment with the α-adrenergic-blocking agent, phentolamine, potentiated the decreases in the renal...

... of the artery are responsive to norepinephrine (NE), 5-hydroxytryptamine (5HT) and vasopressin (VP) at low concentrations, but at the maximal frequency of transmural electrical stimulation used (16 Hz), the response is only 10–20% of the NE maximum response. Phentolamine (2.7 x 10 –6 M ) antagonized responses...

.... In fact, the mean value of the integrated areas of vasodilatation which was 66 ± 8 mm Hg/min in the control condition, was reduced to 45 ± 4 mm Hg/min after administration of atropine in the gracilis artery; meanwhile the integrated areas of systemic hypertension did not show any change. Phentolamine...

...Jorge Castro-Tavares Phentolamine was used as a pure α-adrenergic blocking agent in the study of the arterial plasma potassium responses to adrenergic stimulation in dogs. Both the hyperkalemia and hypokalemia evoked by the intravenous infusion of noradrenaline, 5 μ g/kg·min –1 , were reduced...

...R. Jaques; H. Helfer Both the α -adrenergic blocking agent, phentolamine, as well as the β -blocker, propranolol, inhibited the writhing elicited by AAP, whereas another β -blocking agent possessing the same blocking action on blood-pressure as propranolol, oxoprenolol, was devoid...

..., and vasopressin release. Administration Phentolamine of various β -adrenergic blocking drugs, either intraarterially or intraventricularly, did not alter central angiotensin activity in a manner which could be correlated with β -adrenergic blockade. Local anesthetics inhibited central angiotensin pressor...

... and beta receptors, was inhibited by mixture of phentolamine (10" to 10" g/ml) and propranolol (10" to 10" g/ml), but once again the block was in­ complete. The sensitivity of the intestine to sympathomimetic agents was reduced by cold storage (fig. 2, top row). Threshold doses for the inhibitory effects...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Atropine Phentolamine MJ 1999 Promethazine Gastric ulcer Pharmacology 2: 14 16 (1969) Atropine Phentolamine MJ 1999 Promethazine Gastric ulcer Effect of Atropine, Phentolam ine...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hormone-induced lipolysis Norepinephrine Adrenergic blocking agents Dichloroisoproterenol Phentolamine Theophylline Cyclic 3’,5’-AMP Adenyl cyclase Pharmacology 2...