... animals. This communication examined CSFp in pentobarbital-anesthetized rats subjected to two pertubations where CSFp had been previously measured in conscious rats. Pentobarbital treatment resulted in marked, qualitative differences after both protocols. Whereas conscious rats responded to a 10-min ICV...

...Fumie Murakami; Tsutomu Araki; Yasuno Kanai; Hiroyuki Kato; Takehiko Fujiwara; Kyuya Kogure We investigated the effects of vinconate and pentobarbital against the alterations in spirodecanone binding in the gerbil striatum and hippocampus 5 h and 7 days after 10 min of cerebral ischemia, using...

...Berit X. Carlson; Helen A. Baghdoyan The present study used saturation binding analyses to test the hypothesis that pentobarbital would differentially increase the affinity of benzodiazepine binding across brain regions. The results showed that there were significant (p < 0.05) regional...

...Farid K.R. Stino A pharmacogenetic model for sensitivity of mice to pentobarbital is being developed by selection for sleep-time response. One generation of divergent selection for long and short sleep-time in mice resulted in a 19% increase in the long-sleep line and a 15 % decrease in the short...

...L. Molinengo; M. Orsetti This study concerns the effects of strychnine and caffeine on ethanol, pentobarbital and atropine-induced depression of mouse motility and of frog spinal reflex. Competitive antagonism was found for the interaction between caffeine and ethanol, caffeine and pentobarbital...

...Norio Hobara; Akiharu Watanabe; Hideo Nagashima Blood ethanol levels following intravenous ethanol administration were much higher during anesthesia with diethyl ether (ether), phenobarbital and pentobarbital than in unanesthetized control rats. Blood acetaldehyde levels were significantly lower...

...Jandira Masur; Maria Judith Ribeiro Rats starved for 70 days, i.e. receiving 60% of food ingested by control rats, showed a shortened sleeping time after ethanol and pentobarbital and a reduction of the catatonic response to haloperidol. Conversely, acute 24 h food deprivation increased barbiturate...

...Jeffrey R. Means; Craig Schnell; Tom S. Miya; William F. Bousquet Studies were undertaken to assess the ability of various in vitro and in vivo pentobarbital-metabolizing systems to reflect modifications in pentobarbital response following treatment with either phenobarbital or SKF 525...

...L. Volicer; Charlotte G. Loew Light surgical anesthesia by urethane, but not by chloralose or pentobarbital, inhibited the rise of blood pressure and compensatory bradycardia caused by single injections of angiotensin. Urethane also diminished the pressor effect of angiotensin infusion even when...

...A.E. Munson; W.C. Rose; S.G. Bradley The data reported demonstrate a synergistic response between the alkylating agents nitrogen mustard, cyclophosphamide, and thio-TEPA, and the barbiturate sodium pentobarbital. The synergistic toxicity found during the 24-hour observation period, occurred only...

...Farid K.R. Stino; Saber S. Samaan; Malak G. Kolta; Kemmy M. Mizinga; Karam F.A. Soliman Divergent selection for pentobarbital sedation-time response was practiced in mice for 9 generations. At the end of 9 generations of selection, the long-sedation-time line (LST) slept an average of 433 min...