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Keywords: Oxamate
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Journal Articles
Oxamate Enhances the Anti-Inflammatory and Insulin-Sensitizing Effects of Metformin in Diabetic Mice
Available to Purchase
Journal:
Pharmacology
Pharmacology (2017) 100 (5-6): 218–228.
Published Online: 21 July 2017
...Mu-chao Wu; Wei-ran Ye; Yi-jia Zheng; Shan-shan Zhang Metformin (MET) is the first-line drug for treating type 2 diabetes mellitus (T2DM). However, MET increases blood lactate levels in patients with T2DM. Lactate possesses proinflammatory properties and causes insulin resistance (IR). Oxamate (OXA...