... anions. The organic anion transporters 1 and 3 (Oat1 and Oat3) are present in renal basolateral membranes, which transport organic anions of pharmacological and physiological interest. This study was designed to evaluate the renal expression and function of Oat1 and Oat3 in rats with vascular...

...Hiroyuki Tanaka; Naoyo Sano; Hajime Takikawa Glucuronide and glutathione conjugates have been reported to be substrates of multidrug resistance protein 2 (Mrp2), whereas sulfates of nonbile acid organic anions have never been reported as substrates of Mrp2. To further examine the substrate...

...Anabel Brandoni; Nora B. Quaglia; Adriana M. Torres The purpose of the present study was to examine in rats the effects of acute bile duct ligation on the expression of the organic anion transporter 1 in the kidney and the consequences of these effects on the systemic clearance of organic anions...

... Naoyo Sano Hajime Takikawa Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan Key Words Bile acids W Organic anions W Phalloidin W Bile salt export pump W Multidrug resistance protein 2 Abstract Phalloidin is known to cause cholestasis by preventing microfilament depolymerization...

.... Erythromycin Vinblastine Biliary excretion P-glycoprotein Organic cations Organic anions Bile acids Original Paper Pharmacology 1999;59:249 256 Received: January 20, 1999 Accepted: May 19, 1999 Effects of Organic Anions and Vinblastine on Biliary Excretion of Erythromycin in Rats Akihiro Sato Hajime...