...Man Si; Jiaxi Xu; Fan Zhang; Chuan Wang; Xiaona Du; Hailin Zhang Background/Aims: The slow component of the delayed rectifier K + current ( I Ks ) is one of the major repolarizing currents in the heart. Yet, the signaling mechanisms for norepinephrine- and angiotensin II-induced modulation of I Ks...

... swimming test Serotonin Dopamine Norepinephrine 23 11 2011 8 12 2011 14 2 2012 © 2012 S. Karger AG, Basel 2012 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized...

...B.J. Adegunloye; O.A. Sofola The differences in the responses of isolated ring segments of aorta and mesenteric artery of rat have been investigated. The aortic rings showed higher sensitivity to norepinephrine than the mesenteric artery rings. On the other hand, the sensitivity of the mesenteric...

... (which lacks the β-hydroxyl group) or either enantiomer of norepinephrine or epinephrine (both of which possess the β-hydroxyl group), indicating that Ser 165 is not involved in the interaction of the catecholamines with the α 2a -adrenoceptor. We have previously shown that mutation of Ser 90 , located...

... in the isolated rat heart. Since the synthetic enzymes for GABA and norepinephrine were in close proximity in atrial tissue, these transmitters may interact under physiological conditions. 4 04 1994 13 06 1994 10 6 2008 © 1994 S. Karger AG, Basel 1994 Copyright / Drug Dosage / Disclaimer...

... release. Electrically stimulated (25 mA, 2-ms pulses, 3 Hz, 1 min) release of [ 3 H]norepinephrine ([ 3 H]NE) or [ 3 H]5-hydroxytryptamine ([ 3 H]5-HT) from 400-µm NTS slices stimulated at 75 min (S 1 ) and 130 min (S 2 ) resulted in S 2 /S 1 release ratios that were not different between normal controls...

... rats, elevated blood pressure induced 5 weeks previously returned to normotensive levels. Pressor responsiveness to angiotensin, vasopressin and norepinephrine in unanesthetized rats was studied after prevention of hypertension in control, low-renal-mass hypertensive (LRM) and low-renal-mass...

... Blood pressure Rat Domperidone Arginine vasopressin Epinephrine Norepinephrine Pharmacology 35: 194-202 (1987) Continuous Intravenous Infusion of LY171555, a Potent Selective D2Receptor Agonist, Lowers Blood Pressure in the Conscious Rat Yu Igarashi, Yiu-Fai Chen, J. Michael Wyss, Marshall D...

...Edward E. Soltis; Peter Field This study investigated the effect of sodium pump activity on vascular smooth muscle responsiveness to norepinephrine (NE) in deoxycorticosterone acetate (DOCA)-salt hypertensive rats. Dose-response curves to NE were generated in normal (5.9 m M ), high (10 m M ) or 0...

...Mark E. Olah; Ralf G. Rahwan This study was undertaken to determine the relative age-dependent responsiveness of the rat aorta to depolarizing (potassium) and receptor-activating (norepinephrine) contractile stimulants, and to the calcium antagonists propyl-methylenedioxyindene (pr-MDI...

...Şule Oktay; Mustafa İlhan The acute potentiating effect of ouabain on norepinephrine (NE) induced contractions of isolated rabbit aorta was investigated. Ouabain, at concentrations of 3 × 10 –7 to 10 –5 mol/l potentiated the vasoconstrictor effect of NE as demonstrated by a shift to the left...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Calcium antagonists Propyl methylenedioxyindene Verapamil Sodium nitroprusside Norepinephrine Acetylcholine...

... in DI rats. Renal α 2 -adrenergic receptors and norepinephrine stores were not altered in DI rats. Adrenal NE stores were significantly elevated in DI rats relative to LE rats. The results of this study suggest that in the absence of AVP, centrally acting α 2 -adrenergic agonists have limited...

...) that was exacerbated by 4 weeks of high salt intake (163 ± 6 mmHg). BEA-treated rats had significant salt-induced increases in urinary norepinephrine excretion and hypothalamic and brainstem norepinephrine content, that were not present in BEA-treated rats drinking tap water or control rats drinking saline. BEA...

... or the elevation of SBP in DOCA-treated rats. Dietary supplementation with Tyr induced a significant elevation in urinary excretion of free dopamine (week 1, 3, 5, and 7) and a decreased excretion of free norepinephrine (week 1) without regard to DOCA treatment. Metabolic reponsiveness (change in colonic...

...Ralph E. Howell; Gerald O. Carrier We examined the effects of magnesium on contractile responses of the rabbit pulmonary artery. The contractile force was determined, after applications of norepinephrine or histamine, in a normal or Ca ++ -free solution containing 0 m M Mg ++ or 1.2 m M Mg...

...Ralph E. Howell; Gerald O. Carrier We examined consecutive contractile responses of isolated rabbit pulmonary arteries during repeated exposures to either norepinephrine, histamine or KCl, with washout and relaxation between trials. For each agonist, EC 50 values remained constant during...

... of these responses was negatively correlated with serum estradiol concentration measured by radioimmunoassay. Urinary norepinephrine output was elevated significantly in treated rats during a 24-hour basal period. During a 2-hour exposure to air at 4 °C, urinary outputs of norepinephrine, epinephrine, and dopamine...

... calculated before (C) and after stimulation with two sequential norepinephrine concentrations: 4 × 10 – 6 M (NE 1 ), 1 × 10 – 5 M (NE 2 ). During each sequence, the PCO 2 of the surrounding and perfusion media were held equal and constant at one of four levels. The following mean R values were obtained:PC0 2...

... (3 × 10 –8 –3 × 10 –7 M ) showed a tendency to augment the contractile responses to norepinephrine; in the middle portions it reversed the relaxant responses to norepinephrine into contractile effects in a concentration-dependent manner. In distal portions, nipradilol significantly decreased...