... to determine the effects of pre-treatment with IVM on myocardial ischemia in both ex vivo and in vivo. Methods: In the ex vivo part, two groups of control and treated rats with IVM (0.2 mg/kg) were examined for cardiac function and arrhythmias by isolated heart perfusion. In the in vivo part, four groups...

... Cinanserin in Two Canine Models of PacingInduced Myocardial Ischemia Key Words Serotonin receptors 5HT2 receptors Myocardial ischemia Myocardium, stunned Abstract Previous studies have indicated that structurally dissimilar serotonin2 (5HT2) antagonists can protect globally ischemic/ reperfused rat hearts...

...Allen W. Gomoll; William A. Schumacher; Martin L Ogletree The dose-related cardioprotective efficacy of the thromboxane A2/prostaglandin endoperoxide (TP) receptor antagonist, ifetroban (BMS-180291), was investigated in an anesthetized ferret model of myocardial ischemia (90 min) followed...

...) improved survival by 55% (n = 64; p < 0.05, compared to the vehicle-treated MI group), whereas the same dose of propranolol (n = 42) had no significant effect on survival. These results indicate that carvedilol reduces myocardial ischemia/reperfusion injury, and significantly improves survival...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Myocardial ischemia Myocardial infarction Potassium channel activators Calcium channel blockers Hemodynamics...

.... Grover Bristol-Myers Squibb Pharmaceutical Research Institute, Department of Pharmacology, Princeton, N.J., USA Effect of the Potassium Channel Opener EMD 56431 on Globally Ischemic Rat Hearts Keywords Myocardial ischemia Potassium channels Coronary flow Cromakalim EMD 56431 Abstract The effect...

... determined during nonobstructed coronary blood flow. Sulphinpyrazone, however, did attenuate the reduction in the ventricular fibrillation threshold occuring during transient myocardial ischemia. G25671, the sulfide metabolite of sulphinpyrazone, failed to alter ventricular refractoriness and ‘nonischemic...

... Department of Pharmacology. Squibb Institute for Medical Research, Princeton N.J., USA Key Words. Dihydropyridines Calcium antagonists Myocardial ischemia Abstract. A comparison was made of the anti-ischemic effects of dihydropyridine calcium antagonists in isolated globally ischemic rat hearts...

.... Myocardial ischemia Thromboxane A 2 U-46619 Coronary flow SQ 30,741 SQ 26,655 Original Papers Pharmacology 1990:41:1-15 © 1990 S. Karger AG. Basel 0031-7012/90/0411-0001 $2.75/0 Direct Myocardial Effects of the Thromboxane A2/ Prostaglandin H 2Agonists U-46619 and SQ 26,655 under Ischemic...

..., Rorer Group R & D Division, Tuckahoe. N.Y., USA Key Words. Diltiazem Regional function Myocardial ischemia Repcrfusion Anesthetized dog Abstract. Diltiazem (750 pg/kg plus 600 pg/kg/h X 1h, i.v.) and vehicle were examined in open-chest anesthetized dogs subjected to 15 min of occlusion...

... Nucleotides following a Brief Period of Low-Flow Global Ischemia in the Isolated Perfused Rat Heart Galen M. Pieper, Garrett J. Gross Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee. Wise.. USA Key Words. Myocardial ischemia Reperfusion Nitrovasodilator Prostacyclin...

.... Griswoldb Departments o f aPharmacology, and bImmunology, Smith Kline and French Laboratories, King of Prussia, Pa., USA Key Words. Propranolol Coronary artery occlusion Creatine phosphokinase Myocardial ischemia Myocardial hypertrophy Rat Abstract. This study was designed to assess the effect...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bepridil Myocardial ischemia Infarct size Isolated heart Calcium...

... to in the content or advertisements. Trimetazidine Myocardial ischemia Glycogen Glycogen phosphorylase Dog Original Papers Pharmacology 32: 72-79 (1986) © 1986 S. Karger AG, Basel 0031-7012/86/0322-007252.75/0 Inhibitory Effect of Trimetazidine on Utilization of Myocardial Glycogen during Coronary...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Carbocromene Coronary occlusion Myocardial ischemia Ventricular fibrillation threshold Canine experiments...

... 04 1981 30 5 2008 Aspartate Anaerobic metabolism Glutamate Isolated cat heart Myocardial ischemia Transamination © 1981 S. Karger AG, Basel 1981 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Myocardial ischemia Propranolol Beta-adrenergic blockade Pharmacology 79: 202 208 (1979) The Role o f Propranolol s...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Digitalis Quinidine Chlorothiazide Ethacrynic acid Propranolol Procaine amide Myocardial ischemia Pharmacology 1: 209-217 (1968) Digitalis Propranolol Quinidine...

...Jon Vincelette; Rene Pagila; Kohichi Kawai; Masaaki Ishii; Yuko Horimizu; Ronald Vergona; Mark E. Sullivan; John Morser; William P. Dole; Yi-Xin Wang Background: Inhibition of rho-kinase has been shown to attenuate vasopressin (AVP)-induced myocardial ischemia measured as S-wave depression...

... or Captopril on Myocardial Infarct Size: Assessment in Canine Models of Ischemia Alone and Ischemia with Reperfusion OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO Key Words Angiotensin-converting enzyme Angiotensin-converting enzyme inhibitor Ramiprilat Captopril Myocardial ischemia Reperfusion injury...