... in the rat hearts of methamphetamine dependence and the intervention mechanisms of rhynchophylline. Materials and Methods: This study detected the expression profile of miRNAs in the methamphetamine-induced rat hearts by microarray and verified the expression of miR-133a-5P and Rho-associated, coiled-coil...

...Yi-Kuei Wong; Ming-Kuan Chou; Yuh-Chiang Shen; Yea-Hwey Wang; Jiin-Cherng Yen; Chieh-Fu Chen; Shi-Kwang Lin; Jyh-Fei Liao Background/Aims: Methamphetamine abuse may produce cognitive impairment. Baicalein, a bioactive flavonoid, has antioxidative, anti-inflammatory and neuroprotective effects...

...Tao Lv; Ye Li; Jinjing Jia; Zhizhou Shi; Jie Bai Background: Methamphetamine is a central nervous system stimulant and is one of the agents most commonly abused by illicit drug users which could induce neuron apoptosis when it is used repeatedly and overdosed. Our previous study demonstrated...

...Matthew L. Banks; Daniel F. Manvich; Rayna M. Bauzo; Leonard L. Howell Background: Cocaine and methamphetamine (METH) are two commonly abused drugs that have behavioral-stimulant properties. These stimulant effects are partially mediated by the dopaminergic system. Recent evidence has suggested...

...Yusuke Hori; Hiroshi Takeda; Minoru Tsuji; Teruhiko Matsumiya The abnormal behaviors induced by methamphetamine (MAP: 1 mg/kg) or phencyclidine (PCP: 10 mg/kg) were measured using behavioral analysis following the microinjection of one of three calcium (Ca) antagonists (nifedipine: Nif, nicardipine...