... against impairment in learning and memory in a severe 3×Tg-AD mice model, at both ages studied, and reduced the size of Amyloid β plaques with preservation of the morphological picture. This neuroprotection appeared mainly in the cortex and hippocampus, associated with reduction in activity of c-jun N...

... have shown effects on memory; however, there are no previous reports on the activity of BZP, BEDA, and DBZP on memory or on a description of their neuropharmacological profile. We evaluated the effects of these compounds on acquisition, formation, and consolidation memory and explored...

...Anahita Torkaman-Boutorabi; Seyed-Milad Hashemi-Hezaveh; Hadi Sheidadoust; Mohammad-Reza Zarrindast The prelimbic region of the medial prefrontal cortex (mPFC) in the brain is crucial for memory. Norepinephrine elicits an important influence on mPFC functions. The stimulation of β-adrenoceptors (β...

...Claire R. Galloway; Evan P. Lebois; Shezza L. Shagarabi; Norma A. Hernandez; Joseph R. Manns Acetylcholine signaling through muscarinic receptors has been shown to benefit memory performance in some conditions, but pan-muscarinic activation also frequently leads to peripheral side effects. Drug...

...Christina G. Benishin; Raymond Lee; Lawrence C H. Wang; Hsin J. Liu Ginsenosides, the saponins of ginseng, are bioactive ingredients which exert many beneficial effects. One ginsenoside, Rb 1 , extracted from North American ginseng ( Panax quinquefolium L.), partially prevents the memory deficits...

...N. Saha; H. Datta; P.L. Sharma The effects of morphine on memory have been shown to be dependent on the strain of animal used and on the experimental parameters. Memory was assessed in a passive avoidance task using Swiss albino (ICRC) mice. Morphine at doses of 1 3 and 10 mg kg –1 was administered...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2-Mercapto-ethanol Brain Dopamine Malondialdehyde Behaviour Memory Ageing Mice Pharmacology 1990;40:343-348 0 1990 S. K a rg e r A G . Basel 0 0 3 1-7012/90/0406...

...B.V. Rama Sastry; Victoria E. Janson; Neelam Jaiswal; Osama S. Tayeb The functional decline of memory in the aging human brain has been partially attributed to defects in cholinergic transmission. Therefore, we have investigated various components of the cholinergic system in cerebra of Fischer 344...

...A. Fossen; O.B. Godlibsen; Y. Loyning; J.F. Dreyfus The influence on memory of 7.5 mg zopiclone, given in single and repeated doses was compared with that of 2 mg flunitrazepam, 5 mg nitrazepam and placebo. Compared with placebo, all three drugs induced some impairment of memory especially after...

..., learning and memory processes. The application of these peptides in the mentally ill awaits further exploration. 23 06 1978 29 5 2008 © 1979 S. Karger AG, Basel 1979 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated...

...Nazanin Malekmohamadi; Parviz Heidari; Mousa Sahebgharani; Mohammad-Reza Zarrindast The effects of antipsychotic drugs sulpiride and clozapine on morphine state-dependent memory of passive avoidance task were examined in mice. Post-training administration of morphine (5 mg/kg) led to state...

...Tourandokht Baluchnejadmojarad; Mehrdad Roghani Intracerebroventricular (ICV) injection of streptozotocin (STZ) causes cognitive impairment in rats. The beneficial effect of naringenin (NAR) was investigated on ICV STZ-induced learning, memory, and cognitive impairment in male rats...

... animals also showed poor retention of memory in elevated plus-maze task paradigm. Chronic quercetin administration significantly reversed reserpine-induced retention deficits. Biochemical analysis revealed that chronic reserpine treatment significantly induced lipid peroxidation and decreased...