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Keywords: Maximal electroshock seizure test
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Journal Articles

Beneficial Combination of Lacosamide with Retigabine in Experimental Animals: An Isobolographic Analysis

Subject Area:
Pharmacology
Jarogniew J. Luszczki, Mirosław Zagaja, Barbara Miziak, Maria W. Kondrat-Wrobel, Katarzyna Zaluska, Paula Wroblewska-Luczka, Piotr Adamczuk, Stanislaw J. Czuczwar, Magdalena Florek-Luszczki
Journal: Pharmacology
Pharmacology (2017) 101 (1-2): 22–28.
https://doi.org/10.1159/000480019
Published Online: 20 September 2017
..., instructions or products referred to in the content or advertisements. Antiepileptic drugs Drug interactions Isobolographic analysis Lacosamide Maximal electroshock seizure test Retigabine Polytherapy with 2 or more antiepileptic drugs (AEDs) has now become a preferred method of treatment...
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Journal Articles

Interactions of MRZ 2/576 with Felbamate, Lamotrigine, Oxcarbazepine and Topiramate in the Mouse Maximal Electroshock-Induced Seizure Model

Subject Area:
Pharmacology
Jarogniew J. Luszczki, Wojciech Danysz, Stanislaw J. Czuczwar
Journal: Pharmacology
Pharmacology (2008) 81 (3): 259–265.
https://doi.org/10.1159/000114870
Published Online: 04 February 2008
... electroshock seizure test in mice. Isobolographic transformation of data revealed that MRZ 2/576 (5 mg/kg, i.p.) exerted barely additive interactions with all investigated antiepileptic drugs in the maximal electroshock seizure test. In conclusion, the isobolographic analysis revealed that MRZ 2/576 additively...
View article titled, Interactions of MRZ 2/576 with Felbamate, Lamotrigine, Oxcarbazepine and Topiramate in the Mouse Maximal Electroshock-Induced Seizure Model
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