... to in the content or advertisements. Glutathione Gastric cytoprotection Ethanol injury Diethyl maleate Buthionine sulfoximine N-Acetyl-L-cysteine L-2-Oxothiazolidine-4-carboxylate Leukotriene Pharmacology 1989;38:57-60 © 1989 S. Kargcr AG. Basel 0031-7012/89/0381-005 7J2.75/0 Role of Glutathione...

...P. Sirois; M. Chagnon; P. Borgeat; P. Vallerand Leukotrienes (LT) LTA 4 , LTB 4 , LTC 4 , LTD 4 and LTE 4 induced marked contractions of guinea pig lung parenchymal strips mounted in organ baths. These contractions were inhibited differentially (40–50% for LTA 4 , LTC 4 , LTD 4 and LTE 4 , and 90...

... in the biosynthesis of eicosanoids such as prostaglandins and leukotrienes. To examine the contribution of cPLA 2 α to skin inflammation, we evaluated the effect of (E)-N-[(2S,4R)-4-[N-(biphenyl-2-ylmethyl)-N-2-methylpropylamino]-1-[2-(2,4-difluorobenzoyl)benzoyl]pyrrolidin- 2-yl]methyl-3-[4-(2,4-dioxothiazolidin-5...

... genes W Oxidative stress W Chemical carcinogen W Prostaglandin W Leukotriene W Basal cell carcinoma W Tissue-specific expression Abstract Two supergene families encode proteins with glutathione S-transferase (GST) activity: the family of soluble enzymes comprises at least 16 genes; the separate family...

... receptors, respectively, in combination with treatment by an antihistaminic and a cysteinyl leukotriene antagonist. SR-48968 but not CP-96345, significantly inhibited the late phase of the bronchial contraction. Phosphoramidon, a neutral endopeptidase inhibitor, tended to potentiate bronchial contraction...