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Keywords: Inhibition
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Journal Articles
Subject Area:
Pharmacology
Pharmacology (2017) 100 (3-4): 139–147.
Published Online: 22 June 2017
... tested at 100 µmol/L, only TBT inhibited pregnenolone-mediated progesterone production in JEG-3 cells by over 50%. Except TTBT, all other 4 fungicides inhibited testosterone-mediated estradiol production by over 50%. TBT was a moderate HSD3B1 inhibitor with a half maximal inhibitory concentration (IC 50...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2017) 99 (3-4): 139–143.
Published Online: 05 January 2017
... disorder when other agents are not effective [ 8 ]. It is metabolized to its major active metabolite, hydroxybupropion, primarily via the CYP2B6 isoenzyme [ 9,10 ]. In vitro [ 9 ] and in vivo studies [ 11,12 ] or case reports [ 13,14 ] have shown that bupropion inhibits CYP2D6 activity. Thus, there exists...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1985) 30 (2): 109–114.
Published Online: 04 June 2008
... of the leukemic cell line, L1210, was inhibited. Other polycations tested did not show this effect. The hexadimethrine had no significant effect on the rejection rate of histoincompatible skin grafts in mice. Low concentrations did inhibit the growth of the L1210 leukemia cells in DBA/2J mice. Pharmacology 30...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1980) 21 (3): 153–160.
Published Online: 30 May 2008
... metabolized exceeds the amoung of PAP recovered. Data suggest that enhancement of p-hydroxylation of aniline by acetone, malaoxon and paraoxon may result from inhibition of further metabolism of PAP by the microsomal cytochrome b 5 -dependent desaturase system, involvement of the desaturase system...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1981) 22 (1): 52–58.
Published Online: 30 May 2008
...Cesare Agostini; Michele Alfisi An extract from bovine muscle, prepared by proteolytic digestion, inhibits the development of CCl 4 -induced liver cirrhosis when administered either subcutaneously or orally to the rat. It has a significant effect on survival time, liver and body weight, and gross...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1980) 20 (1): 27–31.
Published Online: 30 May 2008
... citalopram inhibited 5HT uptake by 30–40% but NA uptake was not affected at any of the concentrations of citalopram studied. At the highest concentrations of citalopram (10 –5 to 10 –4 mol/l) the accumulation of IP and PQ was reduced by 25–30%. It is concluded that at low concentrations, citalopram...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1975) 13 (2): 112–127.
Published Online: 29 May 2008
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Antipyrine Bishydroxycoumarin Drug interactions Halofenate Induction Inhibition Warfarin Pharmacology 13: 112-127...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2004) 72 (4): 247–253.
Published Online: 05 November 2004
...Norio Ogata; Takashi Shibata Wood creosote, a mixture of phenolic compounds, inhibits enterotoxin-induced intestinal fluid secretion, suggesting that one of its constituents suppresses transepithelial Cl – secretion from the intestinal mucosa. To identify an active constituent in wood creosote...