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Keywords: Inflammation
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Pharmacology
Pharmacology (2024) 109 (4): 183–193.
Published Online: 16 March 2024
... and migration of VSMCs can lead to neointimal hyperplasia after vascular injury. Abnormal hyperplasia of neointima and inflammation are one of the main features of atherosclerosis. Therefore, targeting TCF21 may become a potential treatment for relieving atherosclerosis. Key Messages: TCF21 as a member of basic...
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Pharmacology (2023) 108 (3): 286–300.
Published Online: 16 May 2023
... inflammation and barrier function were also evaluated. Results: LAF treatment prevented anorexia and weight loss in rats and ameliorated reductions in hemoglobin, hematocrit, total protein, and albumin levels. LAF reduced the severity of IND-induced intestinal damage including macroscopic and histopathological...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2023) 108 (3): 301–307.
Published Online: 16 May 2023
... somnifera Inflammation Withanolides Alkaloids The therapeutic properties of Withania somnifera (L.) Dunal (WS, family: Solanaceae ) have been widely investigated at pre-clinical and clinical level [ 1 ]. WS extracts (WSEs) were reported to induce beneficial effects on inflammation-based...
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Pharmacology (2023) 108 (2): 166–175.
Published Online: 07 March 2023
... rhinitis Degranulation Inflammation Histamine Allergic rhinitis (AR) is a type I allergy mediated by immunoglobulin (Ig) E, featuring paroxysmal nasal itching, paroxysmal sneezing, a running nose with a profuse watery discharge, as well as nasal congestion [ 1 ]. Current recommended therapies...
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Subject Area:
Pharmacology
Pharmacology (2021) 106 (5-6): 294–304.
Published Online: 18 March 2021
...Naseratun Nessa; Miyuki Kobara; Hiroe Toba; Tetsuya Adachi; Toshiro Yamamoto; Narisato Kanamura; Giuseppe Pezzotti; Tetsuo Nakata Introduction: Periodontitis is a lifestyle-related disease that is characterized by chronic inflammation in gingival tissue. Febuxostat, a xanthine oxidase inhibitor...
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Subject Area:
Pharmacology
Pharmacology (2021) 106 (1-2): 20–28.
Published Online: 04 January 2021
..., IL-6, caspase-3, and caspase-9 in chondrocytes was analyzed by RT-qPCR or Western blot. Results: We found that LPS led to inflammatory responses, cell apoptosis, and increased miR-155 expression in human articular chondrocytes. Tanshinone IIA could inhibit LPS-induced inflammation and cell apoptosis...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2020) 105 (11-12): 639–644.
Published Online: 20 July 2020
...Qianyu Yue; Tian Liu; Zhongfeng Cheng Introduction: Acute lung injury (ALI), a commonly detected syndrome, is characterized by the accumulation of neutrophils and leucocytes, and inflammation of pulmonary tissues. Objective: The present study was designed to investigate the effect and underlying...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2020) 105 (9-10): 491–504.
Published Online: 26 May 2020
...Ji Huang; Chang Liu; Xiu-Fen Ming; Zhihong Yang Background: Adipose tissue inflammation occurs not only in obesity but also in aging and is mechanistically linked with age-associated diseases. Studies show that ablation of the l-arginine-metabolizing enzyme arginase-II (Arg-II) reduces adipose...
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Pharmacology (2021) 106 (1-2): 37–44.
Published Online: 15 April 2020
... oxidative stress, mitochondrial dysfunction, neuro-inflammation, and even apoptosis and cell death. Principally, toll-like receptors (TLRs) could regulate the inflammatory/anti-inflammatory balance in patients with radiation-induced brain injury. Vinpocetine has an anti-inflammatory effect as shown in both...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2020) 105 (9-10): 568–575.
Published Online: 15 January 2020
..., instructions or products referred to in the content or advertisements. Ganoderic acid A Transforming growth factor -β Smad-3 Nuclear factor kappa B Lung fibrosis Inflammation Mouse lung tissues in each group were cut into small pieces and extracted on ice with RIPA buffer (RIPA containing...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2020) 105 (5-6): 272–280.
Published Online: 27 November 2019
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Myocardial infarction Necrosis Oxidative stress Bcl-2 Inflammation The efficient medical services together with increase in awareness for health have enhanced...
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