...Tomoyoshi Miyamoto; Yoshinori Funakami; Erika Kawashita; Shiori Tomita; Ai Nomura; Nanako Sugimoto; Haruka Saeki; Takaya Miyazakia; Maho Tsubota; Seiji Ichida; Atsufumi Kawabata Lipopolysaccharide (LPS) induces hyperthermia accompanied by various other systemic inflammatory symptoms. The rodents...

... in the Rat Key Words Dizocilpine MK-801 Morphine Analgesia Hyperthermia Tolerance Rats Dose response N-methyl-Z>-aspartate receptor Abstract The effect of dizocilpine (MK-801), an N-methylaspartate receptor antagonist, on the development of tolerance to the analgesic and hyperthermic effects of morphine...

.... Morphine Analgesia Hyperthermia Tolerance-dependence Abstinence signs Decay Naloxone Original Paper Pharmacology 1992;45:319-328 Vincent M. Villar Hemendra N. Bhargava Department of Pharmacodynamics (m/c 865), Health Sciences Center. University of Illinois at Chicago, 111.. USA Pharmacodynamics...

... unaffected. Since increased morphine concentrations in serum produced by naltrexone cannot explain its antagonistic effects on analgesia and hyperthermia, it is concluded that naltrexone produces its effects by blocking opiate receptors at the appropriate sites. The increases in serum morphine levels...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Morphine Aging Analgesia Hyperthermia Radioimmunoassay Pharmacology 1991;43:256-263 Analgesic and Thermic...

...S.B. Kandasamy In the rabbit, intracerebroventricular administration of dibutyryl cyclic AMP (DBC) produces fever which is selectively antagonised by phenoxybenzamine. This indicates the involvement of central α-adrenoceptors in DBC-induced fever. The decrease in DBC hyperthermia after 6...

... of methacholine and acetylcholine each produced a dose-dependent hyperthermia in rabbits. The hyperthermia was due to a decrease in both ear skin blood flow and respiratory evaporative heat loss. Furthermore, the effects of methacholine of acetylcholine on body temperature was antagonized by pretreatment...

...William Diamantis; John Melton; Duane Sofia Tetrabenazine evoked a biphasic response in rectal temperature of the rat following intraperitoneal administration of 4.4–70.0 mg/kg. The initial hyperthermia was inversely related to the dose while the subsequent hypothermia was dose-dependent...

... antagonized by pimozide, and also reduced after pretreatment with 6-hydroxydopamine. These results are discussed with regard to the possible role of central dopamine in mediating amphetamine-induced hyperthermia in rats. 29 5 2008 © 1975 S. Karger AG, Basel 1975 Copyright / Drug Dosage...

...H.-H. Frey Hyperthermia was elicited in rats by the subcutaneous injection of 4 mg/kg (+)-amphetamine, 4 mg/kg (+)-p-chloroamphetamine, or 8 mg/kg fenfluramine. This hyperthermia could be abolished by oral pretreatment with 300 mg/kg p-chlorophenylalanine. Cyproheptadine, at a dose of 0.05 mg/kg...

...C. Gardey-Levassort; G. Olive; P. Lechat In rabbits pretreated with i.p. probenecid, the hyperthermia induced by 5-hydroxytryptophan (5-HTP) was markedly potentiated. There was, however, no change in the level of 5-hydroxytryptamine (5-HT) in the hypothalamus and brain stem. Consequently...

...Timothy Othman; Shinji Goto; Jeong-Beom Lee; Akihiro Taimura; Takaaki Matsumoto; Mitsuo Kosaka The antineoplastic agent paclitaxel (PTX), a microtubule-stabilizing agent, is known to arrest cell cycle progression and induce apoptosis. Mild hyperthermia (HT) also disrupts the microtubule system...