...K. Nandy; F.H. Schneider Exposure of mouse neuroblastoma cells in culture to low pH for 8 days caused a sixfold increase in cell lipofuscin pigment. Pigment content was measured as the percent of cells having clumps of acid phosphatase-staining material. Hydergine, bétwen 0.1 and 3 μg/ml, caused...

... laboratories. Since then, worldwide investigations on ergot alkaloids resulted in the elucidation of their structures and total syntheses and preparation of valuable therapeutics such as Methergine, Hydergine, Dihydergot, and others. © 1978 S. Karger AG, Basel 1978 Copyright / Drug Dosage / Disclaimer...

.... Subjective tests are used for disorders of personality and affect. The most useful and practical tests are described in detail. Clinical trials have to be double-blind with strict control of all factors which may influence the tests. Hydergine has been tested in 1,300 patients and shown to be an effective...

...P. Portaleone We compared the effects of bromocriptine and of hydergine on striatal and hypothalamic adenylate cyclase activity. Rats treated with bromocriptine (5 mg/kg) or with hydergine (3 mg/kg), showed a stimulation of adenylate cyclase activity in the striatum, but not in the hypothalamus...