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Keywords: HMG-CoA reductase inhibitors
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Journal Articles

Effects of HMG-CoA Reductase Inhibitors on the Pharmacokinetics of Losartan and Its Main Metabolite EXP-3174 in Rats: Possible Role of CYP3A4 and P-gp Inhibition by HMG-CoA Reductase Inhibitors

Subject Area:
Pharmacology
Si-Hyung Yang, Jun-Shik Choi, Dong-Hyun Choi
Journal: Pharmacology
Pharmacology (2011) 88 (1-2): 1–9.
https://doi.org/10.1159/000328773
Published Online: 25 June 2011
...Si-Hyung Yang; Jun-Shik Choi; Dong-Hyun Choi The present study was designed to investigate the effects of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (atorvastatin, pravastatin, simvastatin) on the pharmacokinetics of losartan and its active metabolite EXP-3174 in rats...
View article titled, Effects of <span class="search-highlight">HMG</span>-<span class="search-highlight">CoA</span> <span class="search-highlight">Reductase</span> <span class="search-highlight">Inhibitors</span> on the Pharmacokinetics of Losartan and Its Main Metabolite EXP-3174 in Rats: Possible Role of CYP3A4 and P-gp Inhibition by <span class="search-highlight">HMG</span>-<span class="search-highlight">CoA</span> <span class="search-highlight">Reductase</span> <span class="search-highlight">Inhibitors</span>
Open the PDF for Effects of <span class="search-highlight">HMG</span>-<span class="search-highlight">CoA</span> <span class="search-highlight">Reductase</span> <span class="search-highlight">Inhibitors</span> on the Pharmacokinetics of Losartan and Its Main Metabolite EXP-3174 in Rats: Possible Role of CYP3A4 and P-gp Inhibition by <span class="search-highlight">HMG</span>-<span class="search-highlight">CoA</span> <span class="search-highlight">Reductase</span> <span class="search-highlight">Inhibitors</span> in another window
Journal Articles

Effect of Atorvastatin on in vitro Expression of Resistin in Adipocytes and Monocytes/Macrophages and Effect of Atorvastatin Treatment on Serum Resistin Levels in Patients with Type 2 Diabetes

Subject Area:
Pharmacology
Yukiko Ichida, Goji Hasegawa, Michiaki Fukui, Hiroshi Obayashi, Mitsuhiro Ohta, Aya Fujinami, Kiyoe Ohta, Koji Nakano, Toshikazu Yoshikawa, Naoto Nakamura
Journal: Pharmacology
Pharmacology (2006) 76 (1): 34–39.
https://doi.org/10.1159/000088948
Published Online: 07 December 2005
... Chemistry, Kobe Pharmaceutical University, Kobe, d Department of Clinical Research Center, Utano National Hospital, and e Department of Internal Medicine, Yamashiro Hospital, Kyoto, Japan Key Words Resistin Adipokines HMG-CoA reductase inhibitors Atherosclerosis Insulin resistance Abstract Resistin...
View article titled, Effect of Atorvastatin on in vitro Expression of Resistin in Adipocytes and Monocytes/Macrophages and Effect of Atorvastatin Treatment on Serum Resistin Levels in Patients with Type 2 Diabetes
Open the PDF for Effect of Atorvastatin on in vitro Expression of Resistin in Adipocytes and Monocytes/Macrophages and Effect of Atorvastatin Treatment on Serum Resistin Levels in Patients with Type 2 Diabetes in another window
Journal Articles

Atorvastatin and Simvastatin Decrease the Uptake of Acetylated Low-Density Lipoprotein by Human Monocytes

Subject Area:
Pharmacology
Anna Tavridou, Vangelis G. Manolopoulos
Journal: Pharmacology
Pharmacology (2005) 73 (2): 102–105.
https://doi.org/10.1159/000081630
Published Online: 05 January 2005
...Anna Tavridou; Vangelis G. Manolopoulos Several lines of evidence indicate that HMG-CoA reductase inhibitors, calcium channel blockers, and angiotensin-converting enzyme inhibitors exert anti-atherogenic effects in vitro and in vivo. In the present study, we determined the effect of members...
View article titled, Atorvastatin and Simvastatin Decrease the Uptake of Acetylated Low-Density Lipoprotein by Human Monocytes
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