... by heart failure. An infant affected by initial congestive cardiac failure, after starting the treatment with enalapril in association with furosemide, developed acute kidney injury (AKI). No underlying renal disease or renal artery stenosis was found. He recovered from kidney injury after the therapy...

...Yuhua Yang; Angela Fu; Xiaosu Wu; Jeff D. Reagan We report that the loop diuretic drugs bumetanide and furosemide used in the treatment of hypertension are GPR35 agonists. We utilized calcium flux, inositol phosphate accumulation, and dynamic redistribution assays to examine the pharmacology...

...R. Babini; P. Larose; A. Lécrivain; P. du Souich The influence of dietary sodium and saralasin on the natriuretic and diuretic response to furosemide (5 mg/kg i.v.) was studied in three groups of conscious rabbits maintained for 4 weeks on either a normal sodium diet (NSD), or a low sodium diet...

... by pretreat-ment with serosal furosemide. It is considered that ADH blocks apical membrane Cl – channels and that angiotensin reverses this effect by increasing apical membrane permeability to Cl – . Amphotericin B reverses the effect of ADH possibly by increasing Na + absorption. 17 02 1987 9 03...

... which involved the transport of p -aminohippuric acid (PAH) and furosemide by vesicles made from basal-lateral membranes of rabbit kidney proximal tubules. Basal-lateral membranes were prepared by differential and ultracentrifugation. The transport was measured by using radiola-belled ( 3 H) organic...

...Ken Tsuchiya; Sei Sasaki; Fumiaki Marumo Direct effect of azosemide on the mouse thick ascending limb of Henle’s loop was examined by the isolated tubules perfusion technique, and the effect was compared with that of furosemide. Azosemide added to the tubular lumen reversibly suppressed the lumen...

...Roberto Colombo; Arnaldo Pinelli The in vivo effects of increased free fatty acid (FFA) plasma levels on the protein binding of furosemide were investigated in 30 adult-onset diabetics and 22 patients suffering from bacterial infections (gram-negative bacilli and gram-positive cocci). In diabetics...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Diuretics Furosemide QSAR Anthranilic acid Pharmacology 26: 172-180 (1983...

...P.A. Schwartz; C.T. Rhodes; D.S. Greene The effect of varying concentrations of sodium oleate on the binding of furosemide to human serum albumin was investigated using continuous ultrafiltration. The furosemide fraction free was 1.37% in the absence of sodium oleate increasing to 3.52...

...A. Greither; S. Goldman; J.S. Edelen; L.Z. Benet; K. Cohn Since patients vary in their response to furosemide, a pharmacokinetic study of this drug was undertaken in 7 patients with severe congestive heart failure. The extent of oral availability, determined by the ratio of areas under the oral...

...David E. Smith; Leslie Z. Benet The purpose of the present study was to determine if furosemide’s active transport process could be saturated at therapeutic concentrations and to define a relationship between furosemide in a measurable sampling compartment and its diuretic effect. The experiments...

... potassium loss did not occur during furosemide-diuresis but in the following period of relative antidiuresis. © 1971 S. Karger AG, Basel 1971 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized...

...S.S. Thorgeirsson; H.A. Sasame; J.R. Mitchell; D.J. Jollow; W.Z. Potter The effects of hepatotoxic doses of acetaminophen and furosemide on the function and composition of hepatic endoplasmic reticulum were compared from 3 to 24 h after administration. Acetaminophen caused a significant decrease...

...F. Holzer; M. Hohenegger This study examines the effects of continuous natriuresis on sodium (Na) and potassium (K) balance in conscious rats. Natriuresis was induced either by sodium chloride (NaCl) perfusions of by NaCl perfusions and furosemide. (1) A daily rise of K and Na excretion occurred...

...Anabel Brandoni; Silvina R. Villar; Adriana M. Torres The possibility of gender differences in the relationship between dose and efficacy of drugs has historically been limited. The aim of the present study was to evaluate the influence of sex on the pharmacodynamics of furosemide (FUR) in adult...