... compound, against free fatty acid (FFA)-induced lipotoxicity in a cellular model of steatosis. Methods: HepG2 cells were incubated with 1 mmol/l FFAs together with MGL for 24 h. Cell viability was assessed using the MTT assay. Cell apoptosis was determined by Hoechst staining. Intracellular lipids were...

... 14 04 1986 4 6 2008 ACTH treatment Stress Insulin Glucose Triglyceride Free fatty acids © 1986 S. Karger AG, Basel 1986 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced...

...Roberto Colombo; Arnaldo Pinelli The in vivo effects of increased free fatty acid (FFA) plasma levels on the protein binding of furosemide were investigated in 30 adult-onset diabetics and 22 patients suffering from bacterial infections (gram-negative bacilli and gram-positive cocci). In diabetics...

...% in the presence of 2 mEq/l of sodium oleate. Furosemide bound to two types of binding sites on the albumin molecule. It was found that the numbers of binding sites of each type were constant with the addition of free fatty acid (FFA); however, the decrease in the affinity constants for each site was directly...

...Olof Borgå; Anders Juhlin-Dannfeldt; Rune Dahlqvist Five healthy subjects performed submaximal physical exercise approximately 20 h after a single oral dose of phenytoin (5 mg/kg of the sodium salt). The plasma levels of free fatty acids (FFA) increased 2- to 3-fold in the post-exercise period...

... with pharmacokinetics in human subjects after oral administration of clofibrate. Both clofibrate and free fatty acids (FFA) are extensively bound to circulating plasma proteins. When plasma FFA were elevated to about 2,000 μEq/l, the CPIB elimination half-life decreased from 19.3 h in controls to 7.3 h. Thus, elevation...

... fatty acids Glucose Insulin Prostaglandin A 1 Reserpine Pharmacology 9: 159 163 (1973) Effects of Hypotensive Doses of Prostaglandin A, on Plasma Glucose, Free Fatty Acids and Insulin in Reserpinized Dogs L. Sacca, F. Rengo, G. Perez, M. Chiariello and M. Coitdorelli' Institute of Special...

...Roland Gugler; Don W. Shoeman; Daniel L. Azarnoff Warfarin and diphenylhydantoin (DPH) were displaced from plasma proteins in rats by in vivo elevation of free fatty acids (FFA) produced by exercise or by i.p. injection of d,l-epinephrine (2 mg/kg). In controls FFA were 540 ± 34 μEq/l, binding...