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Keywords: Enzyme inhibition
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Journal Articles
Subject Area:
Pharmacology
Pharmacology (2018) 102 (1-2): 81–87.
Published Online: 28 June 2018
.... Folpet Captan Captafol Enzyme inhibition Aromatase Folpet (IUPAC: 2-[(trichloromethyl)sulfanyl]-1H-isoindole-1,3[2H]-dione), captan (IUPAC: 2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3[2H]-dione), and captafol (IUPAC: 2-[(1, 1, 2, 2--tetrachloroethyl)sulfanyl]-3a,4,7,7a...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2017) 100 (5-6): 301–307.
Published Online: 19 August 2017
... ]. The active metabolite 4'-hydroxyphenyl carvedilol may contribute to carvedilol clinical effects, being 13 times more potent than carvedilol for the beta-blocking effect [ 7 ]. Carvedilol Citalopram Pharmacokinetics Cytochrome P450 Preclinical study Rat liver microsomes Enzyme inhibition ©...
Journal Articles
Pharmacology (2016) 97 (1-2): 10–17.
Published Online: 14 November 2015
.... Steroids Butylated hydroxyanisole Enzyme inhibition Glucocorticoid metabolism 11β-hydroxysteroid dehydrogenase Moreover, HSD11B2 is thought to be the gate-keeper for mineralocorticoid receptors [ 6 ]. Usually, mineralocorticoid receptors have no selectivity for aldosterone (a natural...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2015) 95 (3-4): 145–153.
Published Online: 31 March 2015
... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cytochrome P450 enzyme Enzyme inhibition Methoxychlor 2,2-bis( p -Hydroxyphenyl)-1,1,1...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1993) 47 (5): 318–329.
Published Online: 10 June 2008
... enzyme whether administered orally or parenterally. Enzyme inhibition by either route results in diminished uptake of 59 Fe from radiolabelled heme in the gut. Since tin-mesoporphyrin stimulates excretion of unmetabolized heme into bile its ability to inhibit intestinal heme oxygenase and to decrease...