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Keywords: Displacers
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Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1982) 24 (4): 248–252.
Published Online: 30 May 2008
... not normalize, the binding defect in uremic plasma. On the other hand, charcoal treatment brought the binding of diazepam in uremic plasma to normal values. It seems that only drug binding site I is carbamylated in uremia, while competitive displacers bind to sites I and II. © 1982 S. Karger AG, Basel 1982...