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Keywords: Diabetes mellitus
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Journal Articles
Subject Area:
Pharmacology
Pharmacology (2023) 108 (1): 47–60.
Published Online: 12 January 2023
... the proteasome activity. Methods: Cardiomyopathy was induced in streptozotocin-treated diabetes mellitus (DM) and db/db mice. Luteolin (20 mg kg −1 ·day −1 ) was administrated via gavage for 12 weeks. In vitro , high glucose and high insulin (HGI, glucose at 25.5 mM and insulin at 0.1 µM) inducing primary...
Journal Articles
Journal Articles
Pharmacology (2016) 98 (3-4): 134–170.
Published Online: 02 June 2016
...Harumi Okuyama; Peter H. Langsjoen; Naoki Ohara; Yoko Hashimoto; Tomohito Hamazaki; Satoshi Yoshida; Tetsuyuki Kobayashi; Alena M. Langsjoen Background: Positive associations have been observed between cardiovascular disease (CVD) and type 2 diabetes mellitus (DM), but their causal relationship has...
Journal Articles
Pharmacology (2011) 88 (5-6): 275–283.
Published Online: 04 November 2011
...Azza M. Baraka; Maha M. Deif Background: The potential utility of 5′-adenosine monophosphate-activated protein kinase (AMPK)-activating agents, such as metformin, in inducing angiogenesis, could be a promising approach to promote healing of gastric ulcers complicated by diabetes mellitus. The aim...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2009) 84 (1): 24–28.
Published Online: 28 May 2009
.... Conclusion: These results suggest that the Rho-kinase-mediated pathway plays an important role for 5-HT-induced contraction in diabetic corpus cavernosum tissues. 4 12 2008 3 10 2009 28 5 2009 Diabetes mellitus Corpus cavernosum, human Rho-kinase Serotonin © 2009 S. Karger AG...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1996) 52 (5): 292–302.
Published Online: 10 June 2008
... F.P.J. Diecke E. Cruz Departments of Physiology and Ophthalmology, UMDNJ-New Jersey Medical School, Newark, N.J., USA Zopolrestat Prevention of Proteinuria, Albuminuria and Cataractogenesis in Diabetes mellitus Key Words Albumin Aldose reductase inhibitors Cataract Diabetes mellitus Kidney Na-K-ATPase...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1996) 52 (3): 145–152.
Published Online: 10 June 2008
..., instructions or products referred to in the content or advertisements. Antihyperglycemic drug Antihyperlipidemic drug Diabetes mellitus Hydrochlorothiazide Metformin Plasma glucose Plasma lipids Pyrazinoylguanidine Pharmacology Original Paper Pharmacology 1996;52:145-152 Yousifl. A-Rahim Karl H...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1996) 52 (3): 135–144.
Published Online: 10 June 2008
.... Antihyperglycemic drug Antihyperlipidemic drug Diabetes mellitus Hydrochlorothiazide Metformin Plasma glucose Plasma lipids Pyrazinoylguanidine Pharmacology Original Paper Pharmacology 1996;52:135-144 Yousifl. A-Rahim Karl H. Beyer, Jr. ElliotS. Vesell Department of Pharmacology, Pennsylvania State...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1996) 53 (3): 151–159.
Published Online: 10 June 2008
... Indomethacin Nitric oxide Diabetes mellitus Pharmacology Original Paper Pharmacology 1996;53:151-159 Hassan El-Kashef Department of Pharmacology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt Hyperglycemia Increased the Responsiveness of Isolated Rabbit's Pulmonary Arterial Rings to Serotonin...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1996) 53 (4): 197–210.
Published Online: 10 June 2008
.... Pyrazinoylguanidine Cyclic AMP Diabetes mellitus Lipolysis Adipocytes Pharmacology Original Paper Pharmacology 1996;53:197-210 Yousifl. A-Rahim Karl H. Beyer, Jr. ElliotS. Vesell Department of Pharmacology, Pennsylvania State University College of Medicine, Hershey, Pa., USA Studies on Pyrazinoylguanidine 3...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1997) 54 (5): 256–260.
Published Online: 10 June 2008
....* Elliot S Vesell Studies on Pyrazinoylguanidine 6. Prevention of Cataracts in STZ-Diabetic Rats Department of Pharmacology, The Pennsylvania State University College of Medicine, Hershey, Pa., USA Key Words Pyrazinoylguanidine STZ rats Cataracts Diabetes mellitus Eye Abstract This study was designed...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1995) 50 (2): 69–73.
Published Online: 10 June 2008
... of Medicine and Gunma Prefectural College of Medical Science. Maebashi, Japan Keywords Nitric oxide Streptozotocin Insulin Diabetes mellitus Involvement of Spontaneous Nitric Oxide Production in the Diabetogenic Action of Streptozotocin Abstract The exact mechanism by which streptozotocin (STZ) destroys...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1991) 42 (3): 177–180.
Published Online: 06 June 2008
... and glutamic pyruvic transaminase activity observed when either drug was given alone. These results suggest that administration of thiazide diuretics to treat edema encountered during anti-inflammatory steroid therapy may increase the risk of diabetes mellitus, atherosclerosis and certain thrombotic disorders...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1992) 45 (5): 285–291.
Published Online: 06 June 2008
...A. Beyer-Mears; F.T. Murray; E. Cruz; J. Rountree; M. Sciadini Diabetic nephropathy leading to kidney failure is a major complication of type I (insulin-dependent) diabetes mellitus and is associated with progressive proteinuria. In the present 6-month study, effects of two structurally dissimilar...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1992) 45 (2): 90–98.
Published Online: 06 June 2008
...Jin Qi; Robert M. Curley; John A. Belis The effect of diabetes mellitus on intracellular calcium concentration was measured in single rat bladder smooth muscle cells using the fluorescent calcium indicator dye fura-2 AM. Techniques were developed for isolation and short-term culture of rat bladder...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1993) 46 (2): 101–108.
Published Online: 06 June 2008
...Soosaiah Gunasekaran; Judith A. Young; Thomas E. Tenner, Jr. The present study was undertaken to compare the cardiomyopathies induced by experimental diabetes mellitus and chronic isoproterenol (ISO) pretreatment on inotropic reactivity of right ventricular strips from rats. One month after...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1988) 36 (3): 188–197.
Published Online: 05 June 2008
...A. Beyer-Mears; M. Del Val; E. Cruz; F.T. Murray Proteinuria, a complication of both diabetes mellitus and hypertension, was compared in 2 genetically induced models: insulin-dependent diabetic BB rat (BB), and Okamoto-Aoki spontaneously hypertensive Wistar rats (SHR). Both disease states were...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1988) 36 (2): 112–120.
Published Online: 05 June 2008
...A. Beyer-Mears; F.T. Murray; M. Del Val; E. Cruz; M. Sciadini Sorbinil, an aldose reductase inhibitor, was examined as a therapeutic agent to arrest and/or reverse proteinuria in ‘type 1’ insulin-dependent BB rats having spontaneous diabetes mellitus. Prior to sorbinil treatment, diabetic rats...