...Shenshen Zhu; Jin-Hua Liu This study was conducted to explore the effect of zerumbone, isolated from Zingiber zerumbet Smith, on apolipoprotein A-I (apoA-I)-mediated cholesterol efflux from THP-1 macrophages. THP-1 macrophages were treated with different concentrations (10-100 μmol/l) of zerumbone...

... investigated the effect of aspirin on this process. Methods: The expression levels of ABCA1 in RAW264.7 cells were determined using reverse transcription polymerase chain reaction and Western blot analysis. 3 H-cholesterol efflux was measured by scintillation counting. Results: 0.5 mmol/l aspirin increased...

... metabolism. Despite preferential accumulation in adipose tissue, it is not clear whether the actions of niacin on cholesterol efflux from adipocytes contribute to its HDL-raising effect. Methods: Fully differentiated 3T3-L1 adipocytes were incubated in the medium containing various concentrations of niacin...