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Keywords: Carbachol
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Journal Articles
Subject Area:
Pharmacology
Pharmacology (1997) 54 (6): 298–304.
Published Online: 10 June 2008
... led to a significant delay of gastric emptying rate with respect to vehicle-treated rats. Gastric longitudinal and circular muscle strips of L-NAME or indometacin-treated rats showed a reduction in contractile responses to carbachol. The results demonstrate that NO synthase blockade and indometacin...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1994) 49 (2): 69–74.
Published Online: 10 June 2008
... Tolbutamide Neuroblastoma Astrocytoma ATP-sensitive K+channel Cell growth Brain tumor Diazoxide Carbachol Intracellular Ca2+ Abstract The effect o f cromakalim, a K+ channel opener, on the growth o f human brain tumor cells was investigated. Cromakalim inhibited the growth o f SK-N-MC human neuroblastoma...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1991) 42 (1): 23–27.
Published Online: 06 June 2008
... of the compounds to inhibit the negative inotropic response to carbachol in the isolated left atrium of the rat. Bornaprine showed a pA 2 value (concentration required to reduce the agonist response by 50%) of 7.27 ± 0.21. The exo and endo epimers were approximately equipotent in this regard. One metabolite, the 5...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1990) 41 (2): 75–81.
Published Online: 05 June 2008
...Larry A. Walker; James N. Rider; Alan B. Jones This study evaluated the changes in renal function that occur during the early phases of chronic infusion of carbachol into the lateral ventricle in conscious rats. Infusion of 1.0 µg/h of carbachol i.c.v. resulted in a prompt pressor response...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1984) 28 (2): 112–120.
Published Online: 04 June 2008
...Waldemar A. Turski; Stanistaw J. Czuczwar; Lechostaw Turski; Maria Sieklucka-Dziuba; Zdzisław Kleinrok In an attempt to elucidate the mechanism of wet dog shakes (WDS) produced by carbachol administered into the rat lateral brain ventricle, the effects of blockade of muscarinic and nicotinic...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1986) 32 (5): 257–267.
Published Online: 04 June 2008
...Bo Hellman; Erik Gylfe Exposure to carbachol resulted in a biphasic stimulation of 45 Ca efflux when β-cell-rich pancreatic islets from ob/ob mice were perifused with a Ca 2+ -deficient medium. The pattern of stimulated 45Ca efflux was markedly modified by glucose. Whereas the initial carbachol...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1969) 19 (3): 163–164.
Published Online: 29 May 2008
...K. Süsskand; K.-F. Sewing In the guinea-pig isolated atrium pirenzepine shifts the concentration response curve of carbachol on frequency towards the right thus indicating that pirenzepine has anticholinergic properties. Guinea pig Atrium Carbachol Pirenzepine 29 01 1979 2 03...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1973) 10 (5): 298–305.
Published Online: 28 May 2008
...Dennis J. Foley; Robert E. Stitzel; Joseph J. Mc Phillips Repeated injections of the cholinesterase inhibitor disulfoton to female rats cause subsensitivity of the ileum to the spasmogenic action of carbachol. A slight degree of subsensitivity appeared after the second injection and sub sensitivity...
Journal Articles
Journal Articles