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Keywords: Cannabidiol
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Journal Articles
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1984) 29 (6): 343–350.
Published Online: 04 June 2008
...S.K. Tilak; A.M. Zimmerman Effects of Δ9-tetrahydrocannabinol (THC), cannabinol (CBN) and cannabidiol (CBD) (1, 3 or 5 μ M for 2 h) on macromolecular synthesis were investigated in homogeneous populations of pachytene spermatocytes and round spermatids obtained from CD-1 mice. Incorporation of 3H...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1980) 21 (4): 277–287.
Published Online: 30 May 2008
...), cannabinol or cannabidiol at a dose of 10 mg/kg, the percentage of micronuclei in cannabinoid-treated mice was 3- to 5-fold greater than in the dimethyl sulfoxide controls. In the acute series, polychromatic erythrocytes were scored after a single exposure. In one acute series there was an approximately...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1980) 21 (3): 175–185.
Published Online: 30 May 2008
...Jomar M. Cunha; E.A. Carlini; Aparecido E. Pereira; Oswaldo L. Ramos; Camilo Pimentel; Rubens Gagliardi; W.L. Sanvito; N. Lander; R. Mechoulam In phase 1 of the study, 3 mg/kg daily of cannabidiol (CBD) was given for 30 days to 8 healthy human volunteers. Another 8 volunteers received the same...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1968) 18 (3): 143–148.
Published Online: 29 May 2008
... with cannabidiol (CBD) was not statistically different from the control value. The relative toxicity of the cannabinoids in these studies was Δ 9 -THC > CBN > CBD. Normal sperm have a smooth kidney-shaped head with a prominent hook; abnormal sperm have shapes which include heads without hooks, banana-shaped...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1978) 16 (4): 199–205.
Published Online: 29 May 2008
... be that the response depression reflects changes in this curve. Rats were tested on VI performance at five levels of food deprivation and were treated with a vehicle control, marijuana extract distillate (MED) at 7.5 and 11.25 mg/kg, cannabidiol (CBD), at 15 mg/kg or combinations: 7.5 mg/kg MED + 15 mg/kg CBD...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1978) 16 (6): 333–343.
Published Online: 29 May 2008
..., and cannabidiol did not induce unscheduled DNA repair synthesis in cultured human fibroblasts. Moreover, THC did not suppress UV-induced DNA repair synthesis. 5 07 1977 29 5 2008 © 1978 S. Karger AG, Basel 1978 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1977) 15 (1): 10–23.
Published Online: 28 May 2008
... but not for cannabidiol at 25 mg/kg or cannabinol at 25 mg/kg. The mice were given four daily doses (i.p.) of either drug or vehicle (Tween 80-propylene glycol in 1 % saline) or a single injection (i.p.) of sheep red blood cells in addition to four daily doses (i.p.) of drug or vehicle. Suppression of the antigenic...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1974) 11 (3): 146–150.
Published Online: 28 May 2008
...Ivan Izquierdo The anticonvulsant drugs, cannabidiol, phenobarbital, diphenylhydantoin and trimethadione, raise the number of stimuli at a 10-sec rate to the fornix needed to cause a hippocampal seizure discharge. The possible value of this test as a method for the assay of antiepileptic agents...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1974) 11 (3): 139–145.
Published Online: 28 May 2008
...Mario Tannhauser; Iván Izquierdo Epileptogenic stimulation of the fornix during 25 min caused a fall of total hippocampal RNA concentration in rats. This fall was prevented by the preadministration of phenobarbital, trimethadione, diphenylhydantoin or cannabidiol, which, however, were unable...