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1-15 of 15
Keywords: Caffeine
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Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (2010) 86 (2): 73–78.
Published Online: 17 July 2010
..., it was hypothesized that repeated treatment with the adenosine antagonist caffeine could sensitize D2 dopamine-mediated rotational behavior. Methods: Rats were unilaterally lesioned with 6-hydroxydopamine (6-OHDA), and pretreated (primed) with 3 injections of caffeine or water. One week later, rats were challenged...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1993) 47 (3): 145–151.
Published Online: 10 June 2008
...M.A. Noguera; M.P. D’Ocon Serotonin 1 μmol/l induces a contractile response in the isolated rat aorta in both the presence or absence of extracellular Ca. The present study analyzes the influence of temperature and caffeine on subsequent serotonin-induced contractions. In Ca-free medium...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1991) 42 (6): 309–321.
Published Online: 06 June 2008
...John W. Daly; Izumi Hide; Christa E. Müller; Mah Shamim Caffeine and analogs that contain ethyl, propyl, allyl, propargyl and other substituents in place of methyl at 1-, 3- and 7-positions were antagonists at the two major classes (A 1 and A 2 ) of adenosine receptors. Potency at both receptors...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1988) 36 (5): 331–339.
Published Online: 05 June 2008
...Wing-Tai Cheung; Chi-Ming Lee; Tzi-Bun Ng The effect of chronic caffeine treatment on lipolysis in rat epididymal adipose tissue was studied. There was a decrease in body weight, epididymal fat pad weight and mean adipocyte diameter in caffeine-treated rats when compared with control rats...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1983) 27 (1): 50–57.
Published Online: 04 June 2008
...L. Molinengo; M. Orsetti This study concerns the effects of strychnine and caffeine on ethanol, pentobarbital and atropine-induced depression of mouse motility and of frog spinal reflex. Competitive antagonism was found for the interaction between caffeine and ethanol, caffeine and pentobarbital...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1982) 25 (5): 250–261.
Published Online: 04 June 2008
.... The current study demonstrates that the calcium channel blocker, D-600, antagonizes the membrane stabilizing influence of calcium in isolated strips of rat tail artery. Contraction of the arterial strips was induced by application of methoxamine, KCl or caffeine. During the plateau phase of the methoxamine...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1975) 13 (3): 252–259.
Published Online: 29 May 2008
..., caffeine, thiopental, and chlorpromazine by enhancing their level in the brain. Peptides from 120 min digestion were more effective. A possible mechanism of observed changes has been discussed. 22 11 1974 29 5 2008 © 1975 S. Karger AG, Basel 1975 Copyright / Drug Dosage / Disclaimer...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1975) 13 (3): 228–233.
Published Online: 29 May 2008
...William F. Geber; Stanley S. Lefkowitz; Chung Y. Hung The ability of ascorbic acid, sodium salicylate, and caffeine to alter the circulating serum level of interferon was investigated in mice. The animals were singly injected subcutaneously with one of the compounds, 4–8 h later again singly...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1973) 10 (1): 19–27.
Published Online: 28 May 2008
...C.-P. Siegers Oral doses of caffeine (10, 50 or 100 mg/kg) given to rats together with paracetamol (200 mg/kg p.o.) inhibited paracetamol absorp tion and thus lowered the serum concentrations of paracetamol. This caf feine action was dose-dependent and similar to that on blood alcohol levels...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1974) 12 (1): 20–31.
Published Online: 28 May 2008
... specific membrane receptors (KCl) with ID 50 s of 1.8 X 10 –5 M to 3.4 X 10 –5 M. Responses to caffeine, an agent that releases Ca ++ from the sarcoplasmic reticulum, were competitively antagonized by TMB-8. These findings and the demonstration of an attenuation of TMB-8 inhibition of KCl responses...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1976) 14 (1): 67–75.
Published Online: 28 May 2008
...G. Back; G Seidel; W. Endell In rats, pretreatment with caffeine or ethanol shortens the duration of the harmine tremor and decreases the brain concentrations of this alkaloid. Caffeine and ethanol do not influence the plasma concentration of harmine, its plasma protein binding and its cerebral...
Journal Articles
Subject Area:
Pharmacology
Gerald Zernig, Harriet De Wit, Stefan Telser, Matthias Nienhusmeier, Gudrun Wakonigg, Katja Sturm, Iris Berger, Georg Kemmler, Alois Saria
Journal:
Pharmacology
Pharmacology (2004) 70 (4): 206–215.
Published Online: 04 March 2004
... and serves as a reinforcer in animal experiments, both suggesting that BUP may possess some abuse liability. The present study examined if BUP produced subjective effects indicative of abuse liability in a quasi-naturalistic setting, with caffeine (CAF) serving as a positive control. In a randomized double...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (2004) 70 (3): 160–168.
Published Online: 30 January 2004
... (LHR). Treatment with L -NAME did not alter the contractile response induced by phenylephrine; however, indomethacin increased the contraction to phenylephrine only in LHR aortae (1.36 ± 0.08 g, n = 6, vs. 1.97 ± 0.09 g, n = 7). Both phenylephrine and caffeine evoked rapid and phasic contractions...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (2001) 63 (4): 234–239.
Published Online: 06 December 2001
...Martin Sommerauer; Mehmet Ates; Hans Gühring; Kay Brune; Rainer Amann; Bernhard A. Peskar It has been suggested that caffeine can augment analgesic activity and aggravate side effects of nonsteroidal anti-inflammatory drugs (NSAIDs). The aim of the present study was to investigate a possible...
Journal Articles
Subject Area:
Pharmacology
Journal:
Pharmacology
Pharmacology (1998) 57 (6): 295–304.
Published Online: 12 November 1998
... the response to caffeine in Ca 2+ -free medium at 25 and 37°C, and (3) to examine the influence of Mg 2+ and temperature in the release of intracellular calcium induced by 5-HT in Ca 2+ -free medium. Human umbilical arteries were dissected and mounted in organ baths for isometric measurement of force. Our...