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Keywords: Brain
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Journal Articles
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Pharmacology
Pharmacology (2011) 88 (5-6): 284–287.
Published Online: 04 November 2011
... channels and how memantine may be of benefit in AD remains a mystery. Therefore, the investigation of memantine in the mouse, the most commonly chosen subject for modeling AD, has strong potential to lead to better therapies. Here, we present an acute pharmacokinetic analysis of memantine in mouse brain...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1995) 50 (4): 229–237.
Published Online: 10 June 2008
.... It is suggested that the decrease in the ECoG activity several days after ischemia is related to the delayed neuronal damage. PCP is known to protect neurons against this ischemic damage and, therefore, ECoG activity in PCP-treated rats is less reduced than in untreated controls. Brain Electrocorticogram...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1994) 48 (6): 367–373.
Published Online: 10 June 2008
...Oak Za Chi; Hwu Meei Wei; Arabinda K. Sinha; Harvey R. Weiss This study was performed to determine whether nitric oxide (NO) alters the transport of small hydrophilic molecules across the blood-brain barrier in focal cerebral ischemia by administering an NO synthase inhibitor, N G -nitro-L-arginine...
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Journal Articles
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1995) 50 (3): 154–161.
Published Online: 10 June 2008
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. N-Methyl-D-aspartate Anesthesia Halothane Enflurane Diethyl ether n-Alcohols Intracellular calcium Indol Hippocampus Brain Microsacs...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1996) 52 (3): 187–198.
Published Online: 10 June 2008
... adult and neonatal rats. SnMP and CrMP, but not ZnMP, were rapidly cleared from blood and taken up by liver, spleen and kidney where marked inhibition of heme oxygenase activity was demonstrated. None of the metalloporphyrins were detectable in brain, and no inhibition of heme oxygenase activity...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1988) 36 (4): 258–264.
Published Online: 05 June 2008
... observed were increases of brain and liver 2-pyrrolidone. In contrast, regular oral administration for 7 months produced significant increases of GABA and glutamic acid in brain and of glutamic acid alone in liver while GAD decreased in brain and increased in liver; GABA-T was unchanged. A new method...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1987) 34 (2-3): 66–73.
Published Online: 05 June 2008
.... In the cerebral cortex there was a significant decline (p < 0.01) in ChAT activity after the second administration of morphine. These findings indicate that the changes in the responsiveness of the brain cholinergic enzymes following repeated morphine administration may in part explain the rapid development...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1989) 38 (4): 243–252.
Published Online: 05 June 2008
...Hemendra N. Bhargava; Poduri Ramarao; Anil Gulati; George A. Matwyshyn; Rameshwar Prasad The effect of hypothyroidism on the thyrotropin-releasing hormone (TRH) receptors in several brain regions and pituitary of rats was determined. TRH receptors were labeled with 3 H-(3-MeHis 2 )TRH ( 3 H-MeTRH...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1988) 36 (2): 101–105.
Published Online: 05 June 2008
.... Spontaneously hypertensive rats Blood pressure Muscarinic receptors 4-DAMP Brain Pharmacology 36: 101-105 (1988) © 1988 S.Kargcr AG. Basel 0031-7012/88/0362-0101S2.75/0 Blockade of Brain M2 Muscarinic Receptors Lowers Blood Pressure in Spontaneously Hypertensive Rats Henry E. Brezenoff, Hugo Vargas, Yong...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1978) 17 (1): 8–14.
Published Online: 29 May 2008
...Zbigniew S. Herman; Anna Bonczek The influence of 5,7-dihydroxytryptamine (5,7-DHT) and 5,6-dihydroxytryptamine (5,6-DHT) on the level of noradrenaline (NA), dopamine (DA), 5-hydroxytryptamine (5-HT), and 5-hydroxyindoleacetic acid (5-HIAA) in discrete brain areas of mice was studied. Moreover...
Journal Articles
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1971) 5 (1): 55–63.
Published Online: 28 May 2008
...C.-J. Estler; F. Heim; H.P.T Ammon; V. Zimmermann In carbon monoxide poisoned mice enhanced glycogenolysis and lactate production in the brain are not prevented by pretreatment of the animals with reserpine or an adrenergic β- receptor blocking agent (Kö 592). Since, furthermore, glycogenolysis...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1976) 14 (1): 27–38.
Published Online: 28 May 2008
...P. Iwangoff; W. Meier-Ruge; Ch. Schieweck; A. Enz The distribution pattern of 3 H-DH-ergotoxine, labelled by a direct hydration with tritium, was investigated in the cat brain. Apart from the pituitary gland, the brain shows an average DH-ergotoxine concentration of 10 –7 M . A 15 % greater...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (1977) 15 (3): 276–282.
Published Online: 28 May 2008
.... Offspring observed during the preweaning period had a reduction in body, brain and cerebellar weights, as well as in brain length and cerebral and cerebellar widths. Deficits persisted in young rats observed 5½ weeks after cessation of drug exposure and in animals continuing to receive twice daily i.p...
Journal Articles
Subject Area:
Pharmacology
Pharmacology (2002) 65 (4): 193–197.
Published Online: 12 July 2002
... receptors Brain Original Paper Pharmacology 2002;65:193 197 Received: July 9, 2001 Accepted after revision: November 23, 2001 Central Antinociceptive Activity of Acetylsalicylic Acid Is Modulated by Brain Serotonin Receptor Subtypes Maurizio Sandrinia Giovanni Vitalea Luigi Alberto Pinib aDepartment...