...Maho Tsubota; Tomoyoshi Miyamoto; Saki Hiruma; Haruka Saeki; Takaya Miyazaki; Fumiko Sekiguchi; Yoshinori Funakami; Atsufumi Kawabata We examined the effect of repeated cold (RC) stress on cyclophosphamide (CPA)-induced cystitis/bladder pain in mice, in relation to macrophage activity. CPA, given...

... ileum, urinary bladder and trachea (a) confirms the presence of such components of effect (ileum and bladder); (b) indicates TRPV1 involvement in the effect of 5 or 30 µmol/l of P on the basis of an inhibitory action of the antagonist BCTC (ileum); (c) indicates that HC 030031-sensitive TRPA1 receptors...

...John A. Belis; Robert M. Curley; Max Lang The spontaneously diabetic adult male Abyssinian-Hartley guinea pig develops bladder hypertrophy and voiding dysfunction. In contrast to animals with chemically induced diabetes, this animal demonstrates changes in bladder function in the absence...

...Lev Krasnopolsky; Robert M. Levin; Penelope A. Longhurst Bladder strips from sensitized guinea pigs respond to ovalbumin challenge with a contraction accompanied by release of histamine, prostaglandin, and leukotriene. Histamine and prostaglandin release occurs preferentially from the bladder...

... at an average length at which most strips of similar dimensions exhibit their maximal force, and if this method is used to what extent does it underestimate the maximal force generated? When comparing bladder smooth muscle strips 1 cm long from pregnant versus virginal rabbits, the average length at which...

...Gennady Bratslavsky; Catherine Whitbeck; Pat Horan; Robert M. Levin Rabbits were subjected to bilateral ischemia for 3, 6, or 18 h then euthanized and their bladders excised. Isolated strips of rabbit bladder detrusor were incubated in normal Tyrode’s solution and contractile responses to FS...

...Catherine Whitbeck; Mark Barreto; Patrick Horan; Sheila S. Levin; Robert M. Levin Purpose: Studies indicate that bladder hypoxia may be an etiological factor for lower urinary tract dysfunction. Rat and rabbit are two species of experimental animals used frequently to study lower urinary tract...

...Robert M. Levin; Robbert Leggett; Catherine Whitbeck; Patrick Horan The effects of repetitive field stimulation (model of hyperrelexia) on the responses of isolated strips of rabbit urinary bladder to FS and carbachol were evaluated under a variety of incubation conditions. Compared to control...