...Xue Gao; Salman Zeb; Yuan-Yuan He; Yi Guo; Yong-Ming Zhu; Xian-Yong Zhou; Hui-Ling Zhang Introduction: Cerebral ischemia induces reactive proliferation of astrocytes (astrogliosis) and glial scar formation. As a physical and biochemical barrier, the glial scar not only hinders spontaneous axonal...

... extenuates the BPA-induced pain and inflammation by reducing the expression level of proinflammatory cytokines and pain-associated proteins and inhibiting the activity of astrocytes. xwjxiewenji@163.com 1 10 2018 27 12 2018 3 4 2019 © 2019 S. Karger AG, Basel 2019 Copyright...

...Nina Daschil; Stefanie Geisler; Gerald J. Obermair; Christian Humpel Background: It is well established that reactive astrocytes express L-type calcium channels (LTCC), but their functional role is completely unknown. We have recently shown that reactive astrocytes highly express the Ca V 1.2 α 1...

... cell growth factor and heparin. In primary astrocytes, high BSA concentrations induced stress fiber formation, which was reduced by hydrocortisone or the phosphoinositol-3-kinase inhibitor LY294002. In conclusion, high BSA levels are neurotoxic for brain neurons. Cholinergic neurons are protected...

..., was investigated in rat brain, cultured astrocytes and olfactory mucosa. Methods: The isomers were incubated with tissue homogenates, microsomes, or rat liver recombinant UDP-glucuronosyltransferases in the presence of UDP-glucuronic acid. The glucuronides were separated by HPLC and quantitated. Astrocytes were...

... free radicals, and may protect neurons by up-regulating endogenous neurotrophic factors synthesis in the brain. In primary cultured mouse astrocytes, cabergoline 37 µmol/l immediately elevated concentrations of nerve growth factor, brain-derived neurotrophic factor, and glial cell line-derived...